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ProteomicsTotal Proteome Analysis in RNAi treated C. elegans (mrps5, fzo1, drp1, eat3)
A SWATH-based worflow has been developed for C. elegans proteome profiling, including sample preparation, SWATH spectral library generation and downstream data treatment. The influences of several RNAi treatments (including mrps5, fzo1, drp1, eat3) on C. elegans total proteome were studied.
ORGANISM(S): Caenorhabditis elegans 
2020-04-03 | PXD009256 | Pride
Caenorhabditis elegans Mrps-5 Swath Fzo1 Eat3 Drp1 Rnai 
UnknownA membrane-inserted structural model of the yeast mitofusin Fzo1.
Not available
S-EPMC5578988 | biostudies-literature
ProteomicsTime resolved DIA MS analysis of FZO1 depletion in s. cerevisiae
Mitochondrial biogenesis and inheritance must be carefully regulated alongside cell division to ensure proper mitochondrial function and cell survival. The dynamics of the mitochondrial network, including fusion and fission, play a crucial role in mitochondrial inheritance by facilitating the distri...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-03-27 | PXD063340 | Pride
Yeast Dia Spectronaut Fzo1 depletion Lc-ms/ms 
UnknownA mutation associated with CMT2A neuropathy causes defects in Fzo1 GTP hydrolysis, ubiquitylation, and protein turnover.
Not available
S-EPMC2785744 | biostudies-literature
UnknownStructural dataset from microsecond-long simulations of yeast mitofusin Fzo1 in the context of membrane docking.
Not available
S-EPMC6811871 | biostudies-literature
UnknownConnection of the mitochondrial outer and inner membranes by Fzo1 is critical for organellar fusion.
Not available
S-EPMC2195775 | biostudies-literature
UnknownA uvs-5 strain is deficient for a mitofusin gene homologue, fzo1, involved in maintenance of long life span in Neurospora crassa.
Not available
S-EPMC3571291 | biostudies-literature
TranscriptomicsTo analyze the effect of loss of mitochondria on the transcriptome of Candida albicans
This set of experiment was done in order to analyze the effect of a dysfunctional mitochondria on C. albicans. The mutant was obtained by deleting the gene FZO1, which is known to be involved in mitochondrial biogenesis in S. cerevisiae. We show that the deletion of FZO1 leads to a change in mitocho...
ORGANISM(S): Candida albicans 
2013-12-05 | E-GEOD-46003 | biostudies-arrayexpress
TranscriptomicsTo analyze the effect of loss of mitochondria on the transcriptome of Candida albicans
This set of experiment was done in order to analyze the effect of a dysfunctional mitochondria on C. albicans. The mutant was obtained by deleting the gene FZO1, which is known to be involved in mitochondrial biogenesis in S. cerevisiae. We show that the deletion of FZO1 leads to a change in mitocho...
ORGANISM(S): Candida albicans 
2013-12-05 | GSE46003 | GEO
UnknownPlasticity in salt bridge allows fusion-competent ubiquitylation of mitofusins and Cdc48 recognition.
Not available
S-EPMC6861704 | biostudies-literature
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