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TranscriptomicsTranscription profiling by array of siRNA silencing of GABPA in MCF10A cells
The ETS transcription factor GABPA controls cell migration in breast epithelial cells through targeting a cohort of genes, independently from another family member ELK1, and thereby achieves biological specificity. Here, both direct and indirect target genes for GABPA are identified by siRNA silenci...
ORGANISM(S): Homo sapiens 
2013-07-15 | E-MEXP-3682 | biostudies-arrayexpress
ProteomicsGABPA recruits the Integrator endonuclease complex to promote transcription elongation
Transcription factors (TFs) coordinate gene regulatory programs essential for cell identity, yet how individual TFs modulate distinct steps of transcription cycle remains incompletely understood. GA-binding protein alpha (GABPA), an erythroblast transformation specific (ETS)-family TF, is crucial fo...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-04 | PXD068470 | Pride
Intac Gabpa Transcription elongation 
GenomicsGABPA regulates zygotic genome activation and pluripotency formation
GABPA regulates zygotic genome activation and pluripotency formation
PRJNA1096032 | ENA
GenomicsGABPA recruits the Integrator endonuclease complex to promote transcription elongation
GABPA recruits the Integrator endonuclease complex to promote transcription elongation
PRJNA1301416 | ENA
TranscriptomicsChip-chip from Mouse E11.5 distal limb tissue cells for Gabpa, Ets1, Elf1, Etv4, Etv5 antibody
Two different groups of Ets transcription factors differentially act directly at the ZRS to define the spatial expression of Shh in the limb. Chromatin immunoprecipitation (ChIP) of Gabpa, Ets1, Etv4, Etv5 and Elf1 and by ChIP-on-chip analysis demonstrated that with the exception of Elf1 all bind d...
ORGANISM(S): Mus musculus 
2012-02-01 | E-GEOD-33997 | biostudies-arrayexpress
UnknownGABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma.
Not available
S-EPMC5446731 | biostudies-literature
GenomicsThe ETS family member GABPa mediates the development of castrate-resistant prostate cancer (ChIP-Seq)
In prostate cancer, the androgen receptor (AR) is a key transcription factor at all disease stages. We recently showed that during progression to castrate-resistant prostate cancer the AR acquires the ability to bind to a distinct set of genomic sites in tissue samples and that some of the genes tha...
ORGANISM(S): Homo sapiens 
2014-05-21 | E-GEOD-49091 | biostudies-arrayexpress
UnknownHuman Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).
Not available
S-EPMC4839217 | biostudies-literature
UnknownGABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer.
Not available
S-EPMC7244562 | biostudies-literature
UnknownGABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma.
Not available
S-EPMC9097325 | biostudies-literature
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