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INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
The CDK12-INTAC Axis Modulates LEO1 Phosphorylation for Processive Transcription Elongation
INTAC endonuclease and phosphatase modules have distinct roles in transcription (ChP-Seq)
Cyclin-dependent kinase 12 (CDK12) interacts with Cyclin K to form a functional nuclear kinase that promotes processive transcription elongation through phosphorylation of the RNA polymerase II (Pol II) C-terminal domain (CTD). To gain a broader understanding of CDK12 cellular function, we used chem...
ORGANISM(S): Homo sapiens (Human) 
2023-06-08 | PXD038558 | Pride
INTAC endonuclease and phosphatase modules have distinct roles in transcription (TT-Seq)
INTAC endonuclease and phosphatase modules have distinct roles in transcription (PRO-Seq)
Catalytic-independent functions of INTAC confer sensitivity to BET inhibition [CUT&Tag]
Catalytic-independent functions of INTAC confer sensitivity to BET inhibition [RNA-seq]
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