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TranscriptomicsIdentification of dASF/SF2 potential mRNA targets
Deciphering the role of alternative splicing in developmental processes relies on the identification of key genes whose expression is controlled by splicing regulators throughout growth of a whole organism. Targeting expression of five SR proteins in the developing eye of Drosophila allowed us to sh...
ORGANISM(S): Drosophila melanogaster 
2007-09-17 | E-GEOD-5857 | biostudies-arrayexpress
TranscriptomicsIdentification of B52 potential mRNA targets
Deciphering the role of alternative splicing in developmental processes relies on the identification of key genes whose expression is controlled by splicing regulators throughout growth of a whole organism. Targeting expression of five SR proteins in the developing eye of Drosophila allowed us to sh...
ORGANISM(S): Drosophila melanogaster 
2007-09-17 | E-GEOD-5858 | biostudies-arrayexpress
TranscriptomicsIncreased B52 expression does not affect affect global gene expression in Drosophila
Deciphering the role of alternative splicing in developmental processes relies on the identification of key genes whose expression is controlled by splicing regulators throughout growth of a whole organism. Targeting expression of five SR proteins in the developing eye of Drosophila allowed us to sh...
ORGANISM(S): Drosophila melanogaster 
2007-09-17 | E-GEOD-5855 | biostudies-arrayexpress
TranscriptomicsIncreased dASF/SF2 expression does not affect global gene expression in Drosophila.
Deciphering the role of alternative splicing in developmental processes relies on the identification of key genes whose expression is controlled by splicing regulators throughout growth of a whole organism. Targeting expression of five SR proteins in the developing eye of Drosophila allowed us to sh...
ORGANISM(S): Drosophila melanogaster 
2007-09-18 | E-GEOD-5854 | biostudies-arrayexpress
TranscriptomicsRegulation of Vertebrate Nervous System-Specific Alternative Splicing and Development by an SR-Related Protein
Alternative splicing is a key process underlying the evolution of increased proteomic and functional complexity and is especially prevalent in the mammalian nervous system. However, the factors and mechanisms governing nervous system-specific alternative splicing are not well understood. Through a g...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-16187 | biostudies-arrayexpress
GenomicsAn Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [ChIP-Seq]
Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. However, the contribution of AS to the control of embryonic stem cell (ESC) pluripotency is not well understood. Here, we identify an evolutionarily conserved ESC-specifi...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-31006 | biostudies-arrayexpress
TranscriptomicsAn Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [protein binding microarray]
Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. However, the contribution of AS to the control of embryonic stem cell (ESC) pluripotency is not well understood. Here, we identify an evolutionarily conserved ESC-specifi...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-31007 | biostudies-arrayexpress
TranscriptomicsAn Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [RNA-Seq]
Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. However, the contribution of AS to the control of embryonic stem cell (ESC) pluripotency is not well understood. Here, we identify an evolutionarily conserved ESC-specifi...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-30995 | biostudies-arrayexpress
TranscriptomicsAn Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming [AS microarray]
Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. However, the contribution of AS to the control of embryonic stem cell (ESC) pluripotency is not well understood. Here, we identify an evolutionarily conserved ESC-specifi...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-31948 | biostudies-arrayexpress
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