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ProteomicsComplexome profiling to study assembly of complex III in heart tissue from UQCRH deficient mice
UQCRH, also called the hinge protein, is a small subunit of Ubiquinol—cytochrome-c reductase (complex III). Here we used a complexome analysis of heart tissue of UQCRH deficient mice to study complex III assembly and altered supercomplex composition.
ORGANISM(S): Mus musculus (Mouse) 
2021-09-20 | PXD022855 | Pride
Oxidative phosphorylation system Supercomplex formation and stability Complexome profiling Complex iii assembly 
UnknownA robust and reliable non-invasive test for stress responsivity in mice.
Not available
S-EPMC3995076 | biostudies-literature
TranscriptomicsGene regulation in brain, eye and heart of sighted C3H mice
It is unclear what role vision plays in guiding mouse behaviour, since the mouse eye is of comparably low optical quality, and mice are considered to rely primarily on other senses. All C3H substrains are homozygous for the Pde6b(rd1) mutation and get blind by weaning age. To study the impact of the...
ORGANISM(S): Mus musculus 
2010-05-23 | E-GEOD-7855 | biostudies-arrayexpress
UnknownKnockout mice are an important tool for human monogenic heart disease studies.
Not available
S-EPMC10073007 | biostudies-literature
UnknownA rationale for considering heart/brain axis control in neuropsychiatric disease.
Not available
S-EPMC10290621 | biostudies-literature
UnknownPeroxidasin is essential for eye development in the mouse.
Not available
S-EPMC4189897 | biostudies-literature
ProteomicsHeart proteome in Cox10 depending on Opa1 processing
Mitochondrial fusion and fission accompany adaptive responses to stress and altered metabolic demands. Inner membrane fusion and cristae morphogenesis depends on Optic Atrophy 1 (Opa1), which is expressed in different isoforms and is cleaved from a membrane-bound, long to a soluble, short form. Here...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD048804 | Pride
Heart Cox10 Opa1 
UnknownUromodulin retention in thick ascending limb of Henle's loop affects SCD1 in neighboring proximal tubule: renal transcriptome studies in mouse models of uromodulin-associated kidney disease.
Not available
S-EPMC4237372 | biostudies-literature
TranscriptomicsExpression Profiling of Dll1 mutant mouse line
BACKGROUND: The Notch signaling pathway is an evolutionary conserved signal transduction pathway involved in embryonic patterning and regulation of cell fates during development and self-renewal. Recent studies have demonstrated that this pathway is integral to a complex system of interactions, invo...
ORGANISM(S): Mus musculus 
2009-03-01 | E-GEOD-12954 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Dll1 mutant mouse lines on different genetic background
The evolutionarily conserved Delta-Notch cell-cell signal-transduction pathway regulates the determination of various cell fates, which are important for the morphogenesis and development of numerous organs and tissues in many vertebrates and invertebrates. The Dll1 gene was mutated by homologous r...
ORGANISM(S): Mus musculus 
2009-01-01 | E-GEOD-11867 | biostudies-arrayexpress
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