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ProteomicsMouse heart proteomics in Oma1 and Cox10 deficient mice
Cardiomyopathy and heart failure are common manifestations in mitochondrial disease caused by deficiencies in the oxidative phosphorylation system of mitochondria (OXPHOS). Here, we demonstrate that the cardiac-specific loss of the assembly factor Cox10 of the cytochrome c oxidase causes mitochondri...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-27 | PXD031641 | Pride
Mouse Cox10 Heart Cardiomyopathy Oma 
GenomicsSingle nuclei sequencing in wild-type and Cox10-/- regenerating liver.
Single nuclei sequencing in wild-type and Cox10-/- regenerating liver.
PRJNA988489 | ENA
MetabolomicsMitochondrial respiration controls neoangiogenesis during wound healing and tumour growth

The vasculature represents a highly plastic compartment, capable of switching from a quiescent to an active proliferative state during angiogenesis. Metabolic reprogramming in endothelial cells (ECs) thereby is crucial to cover the increasing cellular energy demand under growth conditions. Here w...

2020-06-29 | MTBLS1764 | MetaboLights
GenomicsH3K27ac ChIP-seq in wild-type and Cox10-/- regenerating liver.
H3K27ac ChIP-seq in wild-type and Cox10-/- regenerating liver.
PRJNA987961 | ENA
ProteomicsHeart proteome in Cox10 depending on Opa1 processing
Mitochondrial fusion and fission accompany adaptive responses to stress and altered metabolic demands. Inner membrane fusion and cristae morphogenesis depends on Optic Atrophy 1 (Opa1), which is expressed in different isoforms and is cleaved from a membrane-bound, long to a soluble, short form. Here...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD048804 | Pride
Heart Cox10 Opa1 
GenomicsRNA-seq of wild-type and Cox10-/- muscle stem cells (mouse)
RNA-seq of wild-type and Cox10-/- muscle stem cells (mouse)
PRJNA749782 | ENA
GenomicsCox10-mediated mitochondrial respiration in brown adipocytes regulates adaptive thermogenesis and systemic metabolism
Cox10-mediated mitochondrial respiration in brown adipocytes regulates adaptive thermogenesis and systemic metabolism
PRJNA1402271 | ENA
UnknownPhenotypic assessment of Cox10 variants and their implications for Leigh Syndrome.
Not available
S-EPMC11328382 | biostudies-literature
UnknownThe COX10-AS1/miR-641/E2F6 Feedback Loop Is Involved in the Progression of Glioma.
Not available
S-EPMC8350443 | biostudies-literature
TranscriptomicsSingle nuclei sequencing in wild-type and Cox10-/- regenerating liver.
We report single nuclei sequencing in wild-type and Cox10-/- regenerating mouse livers.
ORGANISM(S): Mus musculus 
2023-07-02 | GSE236043 | GEO
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