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TranscriptomicsComparison of polyribosomal to total transcript profiles
Total and polyribosomal RNA was extracted from rosette leaves of 5-6-week-old wild-type and transgenic Arabidopsis plants (ecotype Col-0). After linear amplification using a modified Eberwine procedure, Cy3- or Cy5-labeled cDNA targets were produced from sense-strand RNA through reverse transcriptio...
ORGANISM(S): Arabidopsis thaliana 
2010-06-09 | E-GEOD-2132 | biostudies-arrayexpress
TranscriptomicsFunctional genomic analysis of a nitrate reductase knockdown relative to wild-type in model-ecosystems (mesocosm)
Current advances in genomics and computational biology have afforded novel insight as to how the phenotype is generated from the genotype – systems biology. We argue that systems biology, when viewed through an ecological lens, provides an unprecedented opportunity to understand how genes cascade th...
ORGANISM(S): Arabidopsis thaliana 
2011-01-01 | E-GEOD-16068 | biostudies-arrayexpress
TranscriptomicsArabidopsis plants exposed to combined heat and drought stress
One of the eminent opportunities afforded by modern genomic technologies is the potential to provide a mechanistic understanding of the processes by which genetic change translates to phenotypic variation and the resultant appearance of distinct physiological traits. Indeed much progress has been m...
ORGANISM(S): Arabidopsis thaliana 
2010-05-26 | E-GEOD-9415 | biostudies-arrayexpress
TranscriptomicsAnalysis of PHOTOPERIOD SENSITIVITY5 Sheds Light on the Role of Phytochromes in Photoperiodic Flowering in Rice
A great majority of plants synchronize flowering with day length. In rice, the most important environmental cue that triggers flowering is the photoperiod. Here, we show that the s73 mutant, identified in a gamma irradiated Bahia collection, displays early flowering and photoperiodic insensitivity d...
ORGANISM(S): Oryza sativa 
2010-05-16 | E-GEOD-16796 | biostudies-arrayexpress
TranscriptomicsParallel Epigenomic and Transcriptomic Responses to Viral Infection in Honey Bees (Apis mellifera)
Here, we examined the transcriptional and epigenetic (DNA methylation) responses to viral infection in honey bee workers. One-day old worker honey bees were fed solutions containing Israeli Acute Paralysis Virus (IAPV), a virus which causes muscle paralysis and death and has previously been associa...
ORGANISM(S): Apis mellifera 
2015-02-06 | E-GEOD-65659 | biostudies-arrayexpress
TranscriptomicsEvidence for Antisense Transcription Associated with microRNAs in Arabidopsis
Exploring miRNA-related antisense transcription in Arabidopsis through RNA transcript profiling of smRNA pathway-defective mutants on a custom high-resolution oligonucleotide array. Two custom arrays were designed with 15,000 oligonucleotide (25-mer and 36-mer) probes in each array. The probes were ...
ORGANISM(S): Arabidopsis thaliana 
2009-04-10 | E-GEOD-15199 | biostudies-arrayexpress
ProteomicsParacrine secretion of monounsaturated fatty acids prevents ferroptosis in triple negative breast cancer and reveals selenocysteine synthesis dependency for metastatic seeding.
The limited availability of therapeutic options for patients with triple-negative breast cancer (TNBC) contributes to the high rate of metastatic recurrence and poor prognosis. Ferroptosis is a cell death caused by iron-dependent lipid peroxidation counteracted by the antioxidant activity of selenop...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-05-17 | MSV000094784 | MassIVE
UnknownGlobal analysis of cancer cell responses to USP9X inhibition
Not available
S-SCDT-10_1038-S44318-026-00742-Y | biostudies-other
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
TranscriptomicsGene expression data for worker honey bees experimentally exposed to a dual infection with Deformed wing virus and Nosema ceranae.
Bees from 3 unrelated colonies were injected with 1ul PBS extract containing 10^9 genome equivalent of Deformed wIng virus (DWV) and/or fed 10µl sucrose solution containing 10^5 fresh Nosema ceranae spores. Control bees were injected and fed with an equivalent DWV- and Nosema-free extract respectiv...
ORGANISM(S): Apis mellifera 
2017-03-08 | E-MTAB-5508 | biostudies-arrayexpress
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