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ProteomicsSWATH proteomic profiling of prostate cancer cells identifies NUSAP1 as a biomarker of response to Galiellalactone
Galiellalactone (GL) is a fungal metabolite that presents antitumor and anti-inflammatory activities in vitro and in vivo. Previous studies have shown that GL targets NF-KB and STAT3 pathways and induces G2/M cell cycle arrest in androgen-insensitive prostate cancer cells. In this study, we show tha...
ORGANISM(S): Homo sapiens (Human) 
2019-01-14 | PXD010993 | Pride
Galiellalactone  cell cycle  prostate cancer  swath  nusap1 
UnknownAnti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice.
Not available
S-EPMC4468253 | biostudies-literature
UnknownGaliellalactone inhibits the STAT3/AR signaling axis and suppresses Enzalutamide-resistant Prostate Cancer.
Not available
S-EPMC6251893 | biostudies-literature
UnknownSTAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population.
Not available
S-EPMC7434889 | biostudies-literature
UnknownGaliellalactone induces cell cycle arrest and apoptosis through the ATM/ATR pathway in prostate cancer cells.
Not available
S-EPMC4826221 | biostudies-literature
UnknownAnti-inflammatory Effects of Fungal Metabolites in Mouse Intestine as Revealed by In vitro Models.
Not available
S-EPMC5545603 | biostudies-literature
MetabolomicsPrevention of acute graft-versus-host disease via single-dose administration of bioengineered extracellular vesicles
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for various hematological and immunologic diseases, but acute graft-versus-host disease (aGVHD) remains a major cause of morbidity and mortality. We previously discovered in patients and murine models that higher le...
2026-09-11 | MTBLS15633 | MetaboLights
MetabolomicsComposition of raw plant-based food items Pilot Study
Not available
ORGANISM(S): Malus domestica/Solanum lycopersicum/Lactuca sativa/Fragaria x ananassa/Allium sativum/Ocimum basilicum 
ST002493 | MetabolomicsWorkbench
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