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Proteomic portrait of human breast cancer progression identifies novel prognostic markers
ORGANISM(S): Homo Sapiens (human) 
2012-12-31 | PAe004809 | PeptideAtlas
Analysis of 104 breast cancer biopsies (removed prior to any treatment with tamoxifen or chemotherapeutic agents) from patients aged between 31 years and 89 years at the time of diagnosis (mean age = 58 years). Twenty were less than 50 years and seventy-seven women were 50 years, or older, at diagno...
ORGANISM(S): Homo sapiens 
Using transgenic mouse models of breast cancer, we demonstrate that loss of ShcA signaling within mammary tumors results in extensive CD4+ T cell infiltration, activation and induction of a humoral immune response. Our studies reveal that ShcA signaling during early breast cancer progression is requ...
ORGANISM(S): Mus musculus 
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