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Assessment of the extent to which the altered profiles of miRNA expression influence viral replication and latency, as well as the efficiency of host defenses, may be useful for understanding the basis of the HIV-1-related alterations in cellular physiology and immunologic control. To this end, thre...
ORGANISM(S): Homo sapiens 
During obesity and type 2 diabetes, pancreatic β-cells face chronic environmental stress, while islet-resident macrophages (iMACs) undergo metabolic reprogramming that exacerbates β-cell dysfunction. Stress-induced cleavage of tRNAs generates tRNA-derived fragments (tRFs), whose role in this context...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-12 | PXD065736 | Pride
During obesity and type 2 diabetes, pancreatic β-cells face chronic environmental stress, while islet-resident macrophages (iMACs) undergo metabolic reprogramming that exacerbates β-cell dysfunction. Stress-induced cleavage of tRNAs generates tRNA-derived fragments (tRFs), whose role in this context...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-12 | PXD073702 | Pride
During obesity and type 2 diabetes, pancreatic β-cells face chronic environmental stress, while islet-resident macrophages (iMACs) undergo metabolic reprogramming that exacerbates β-cell dysfunction. Stress-induced cleavage of tRNAs generates tRNA-derived fragments (tRFs), whose role in this context...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-12 | PXD065726 | Pride
During obesity and type 2 diabetes, pancreatic β-cells face chronic environmental stress, while islet-resident macrophages (iMACs) undergo metabolic reprogramming that exacerbates β-cell dysfunction. Stress-induced cleavage of tRNAs generates tRNA-derived fragments (tRFs), whose role in this context...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-12 | PXD065746 | Pride
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