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UnknownSystemic deuteration of SCID mice using the water-isotopologue deuterium oxide (D2 O) inhibits tumor growth in an orthotopic bioluminescent model of human pancreatic ductal adenocarcinoma.
Not available
S-EPMC10106369 | biostudies-literature
UnknownFAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects.
Not available
S-EPMC2561050 | biostudies-literature
UnknownA Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back to Conjugation-Induced Stiffenings/Loosenings of Rotational Barriers?
Not available
S-EPMC6044500 | biostudies-literature
UnknownNovel purine derivatives mitigate hypoxia ischemia related brain injury through agrin, zyxin and synaptotagmin proteins.
Not available
S-EPMC12491796 | biostudies-literature
UnknownTRPC6 channel translocation into phagosomal membrane augments phagosomal function.
Not available
S-EPMC4664321 | biostudies-literature
UnknownTargeting low molecular weight cyclin E (LMW-E) in breast cancer.
Not available
S-EPMC3855283 | biostudies-literature
UnknownAntihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions.
Not available
S-EPMC2291559 | biostudies-literature
UnknownAntiprion drugs 6-aminophenanthridine and guanabenz reduce PABPN1 toxicity and aggregation in oculopharyngeal muscular dystrophy.
Not available
S-EPMC3044817 | biostudies-literature
Unknown5-Acetamido-1-(methoxybenzyl) isatin inhibits tumor cell proliferation, migration, and angiogenesis.
Not available
S-EPMC9075125 | biostudies-literature
UnknownAntioxidant properties of flavonoid derivatives and their hepatoprotective effects on CCl4 induced acute liver injury in mice.
Not available
S-EPMC9080091 | biostudies-literature
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