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GenomicsInsights into the epigenomic landscape of the human malaria vector Anopheles gambiae
We characterize the epigenome of the human malaria vector Anopheles gambiae in midgut cells by mapping the distribution and levels of two post-translational histone modifications, H3K27ac and H3K27me3. These histone profiles were then correlated with levels of gene expression obtained by RNA-seq. Ch...
ORGANISM(S): Anopheles gambiae 
2014-09-04 | E-GEOD-59773 | biostudies-arrayexpress
TranscriptomicsComparative transcriptome analyses of deltmethrin resistant and suscpetible Anopheles gambiae mosquitoes
we report the RNA-seq based analyses of the transcriptional changes in the Anopheles gambiae mosquitoes from East Africa classified as deltamethrin-resistant or -suscpetible accordign the WHO test comparison of the transcriptome of Anopheles gambiae mosquitoes with phenotypically resistant or suscpe...
ORGANISM(S): Anopheles gambiae 
2012-10-01 | E-GEOD-39269 | biostudies-arrayexpress
TranscriptomicsAnopheles gambiae G3 small RNA sequence: Adult Female Body
We provide a broad overview of sequence diversity in An. gambiae mature microRNAs, including annotation of novel microRNAs identified in this study. Non-coding RNA profiling by high throughput sequencing, in duplicate, using Illumina GAIIx.
ORGANISM(S): Anopheles gambiae 
2014-08-13 | E-GEOD-50396 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of diel and circadian gene expression of the malaria vector Anopheles gambiae
Anopheles gambiae, the primary African malarial mosquito, exhibits numerous behaviors that are under diel and circadian control, including locomotor activity, swarming, mating, host seeking, eclosion, egg laying and sugar feeding. However, little has been performed to elucidate the molecular basis f...
ORGANISM(S): Anopheles gambiae 
2011-06-29 | E-GEOD-22585 | biostudies-arrayexpress
TranscriptomicsTranscriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding
Background: The Anopheles gambiae salivary glands play a major role in malaria transmission and express a variety of bioactive components that facilitate blood-feeding by preventing platelet aggregation, blood clotting, vasodilatation, and inflammatory and other reactions at the probing site on the ...
ORGANISM(S): Anopheles gambiae 
2011-11-01 | E-GEOD-33385 | biostudies-arrayexpress
TranscriptomicsRNA-seq analyses of gene expression changes in the salivary glands of Anopheles gambiae elicited by Plasmodium berghei infection
Salivary glands are the only mosquito tissue invaded by Plasmodium sporozoites being a key stage for the effective parasite transmission and maturation, making knowledge regarding Anopheles sialome highly relevant to understand this process. In this study, we report for the first time a transcriptom...
ORGANISM(S): Anopheles gambiae S 
2015-06-01 | E-MTAB-3415 | biostudies-arrayexpress
TranscriptomicsTranslational regulation of Anopheles gambiae mRNAs in the midgut during Plasmodium falciparum infection
Malaria is caused by Plasmodium parasites, which are transmitted via the bites of infected Anopheline mosquitoes. Midgut invasion is a major bottleneck for Plasmodium development inside the mosquito vectors as a rapidly responding immune system recognizes ookinetes and recruits killing factors from ...
ORGANISM(S): Anopheles gambiae 
2012-09-21 | E-GEOD-38707 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Anopheles gambiae midgut and fat bodies 1 and 11 days post Plasmodium berghei infection to investigate responses in detoxification genes
Detoxification genes were assayed for their response to Plasmodium berghei infection at 1 and 11 days post infection in Anopheles gambiae mosquitoes.
ORGANISM(S): Anopheles gambiae 
2010-08-11 | E-MTAB-195 | biostudies-arrayexpress
TranscriptomicsAnopheles gambiae body parts
The transcriptional profile of four tissues for the multi insecticide Anopheles gambiae (Tiassale) and lab susceptible Anopheles gambiae strain N'Gousso. The malpighian tubules, abodmen integument (containing the fat body epidermal, neuronal, muscle and oenocyte cells), midgut and remaining structur...
ORGANISM(S): Anopheles gambiae 
2014-08-29 | E-MTAB-2808 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of Wolbachia infected Anopheles gambiae Sua5B cells
Wolbachia, an endosymbiotic bacterium, is being investigated as a vector control agent in several insect species. Along with the well known classical reproductive parasitism Wolbachia employs against its host to spread within the population, it is emerging that the bacteria can protect the host agai...
ORGANISM(S): Anopheles gambiae 
2011-03-02 | E-GEOD-23215 | biostudies-arrayexpress
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