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UnknownTargeting Liver Epsins Ameliorates Dyslipidemia in Atherosclerosis through Inhibition of Proprotein Convertase Subtilisin/Kexin Type 9-Mediated Low-density Lipoprotein Receptor Degradation.
Not available
S-EPMC11383288 | biostudies-literature
UnknownPCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage.
Not available
S-EPMC10331474 | biostudies-literature
ProteomicsTriglyceride induces ‌endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity
Triglyceride synthesis promotes the activation of C-type lectin receptors signaling pathway upon fungal infection‌. Triglyceride synthesis induces endoplasmic reticulum lipid bilayer stress and activates the PERK kinase after fungal stimulation. PERK mediates autophagic degradation of SHP-1 to ampli...
ORGANISM(S): Mus Musculus 
2026-01-12 | PXD072975 |
Genomicsena-DATASET-BGI-31-12-2014-03:23:33:590-567 - samples
Gastric Cancer (GC) is a highly heterogeneous disease. To identify potential clinically actionable therapeutic targets that may inform individualized treatment strategies, we performed whole-exome sequencing on 78 GCs of differing histologies and anatomic locations, as well as whole-genome sequencin...
EGAD00001001118 | EGA
GenomicsWGS and WES of 78 pairs Chinese gastric cancer
Gastric Cancer (GC) is a highly heterogeneous disease. To identify potential clinically actionable therapeutic targets that may inform individualized treatment strategies, we performed whole-exome sequencing on 78 GCs of differing histologies and anatomic locations, as well as whole-genome sequencin...
EGAS00001001056 | EGA
UnknownDevelopment of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy.
Not available
S-EPMC7921758 | biostudies-literature
ProteomicsExosomal proteomic profiling revealed children type 1 diabete pathogenesis and potential therapeutic targets
Abstract Introduction: Type 1 diabetes (T1D) is a serious autoimmune disease with high morbidity and mortality. Early diagnosis and treatment remain unsatisfactory. Circulating exosomes containing T1D biomarkers have gained interest, but progress is limited. Objectives: This study investigates mole...
ORGANISM(S): Homo Sapiens 
PXD043146 |
UnknownMultiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Not available
S-EPMC6545280 | biostudies-literature
UnknownPlasma Proteomics to Identify Drug Targets for Ischemic Heart Disease.
Not available
S-EPMC10641761 | biostudies-literature
ProteomicsXopR-mRuby2-TurboID and mRuby2-TurboID AP results in arabidopsis
proteomic data of XopR-mRuby2-TurboID and mRuby2-TurboID labelled proteins
ORGANISM(S): Arabidopsis Thaliana 
PXD051541 |
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