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OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
Lysine acetylation and ubiquitination are one of many protein modifications and play a crucial role in the biological regulation of many organisms, but little is known about the relationship between acetylation and ubiquitination few. Here, the Isw1 protein is an important member of the chromatin re...
ORGANISM(S): Candida albicans (Yeast) 
2022-12-26 | PXD037150 | Pride
Metastatic ability correlates well with the malignance of esophageal squamous cell carcinoma (ESCC). Gaps remain in elucidating the multi-layered interaction networks during ESCC metastasis in the premise of lysine lactylation (Kla) is of crucial importance. Here, we performed an integrated proteoge...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD063341 | Pride
In this study, a label-free quantitative proteomic approach was employed to analyze the serial passaged human skin fibroblast (CCD-1079Sk) cells, within 3305 proteins quantified. Of which, 372 proteins were significantly changed in early passage(P6), middle passage (P12) and later passage (P21), wit...
ORGANISM(S): Homo sapiens (Human) Acyrthosiphon pisum (Pea aphid) 
2018-10-22 | PXD007732 | Pride
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