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ProteomicsIdentification of BRCA2-DSS1 new partner HELZ
R-loops are dynamic three-stranded nucleic acid structures that regulate genome function but can threaten genome stability if not properly resolved. BRCA2, a key player in homologous recombination (HR), also regulates R-loops, though the mechanisms remain unclear. To uncover novel R-loop regulators,...
ORGANISM(S): Homo sapiens (Human) 
2025-12-30 | PXD066766 | Pride
Hela Biotinid-dss1 Brca2 Helz 
ProteomicsUltra-High-Throughput Mapping of the Chemical Space of Asymmetric Catalysis Enables Accelerated Reaction Discovery
The discovery of highly enantioselective catalysts and elucidating their generality face great challenges due to the complex multidimensional chemical space of asymmetric catalysis and inefficient screening methods. Here, we develop a general strategy for ultra-high-throughput mapping the chemical s...
ORGANISM(S): Acyrthosiphon Pisum 
PXD045953 |
ProteomicsiTRAQ proteomics reveals the regulatory response to Magnaporthe oryzae in durable resistant vs. susceptible rice genotypes
Here, we used the iTRAQ method to detect the differentially expressed proteins (DEPs) in the durable resistant rice variety Gangyuan8 (GY8) and the susceptible rice variety Lijiangxintuanheigu (LTH) in response to M. oryzae invasion, and then transcriptome sequencing was used to assist analysisA tot...
ORGANISM(S): Oryza Sativa 
2019-12-09 | PXD016645 |
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