Sort   by:  
 Page size 
ProteomicsIdentification of BRCA2-DSS1 new partner HELZ
R-loops are dynamic three-stranded nucleic acid structures that regulate genome function but can threaten genome stability if not properly resolved. BRCA2, a key player in homologous recombination (HR), also regulates R-loops, though the mechanisms remain unclear. To uncover novel R-loop regulators,...
ORGANISM(S): Homo sapiens (Human) 
2025-12-30 | PXD066766 | Pride
Hela Biotinid-dss1 Brca2 Helz 
GenomicsTranscriptome sequencing of HELZ-null HEK293T human cell line generated by CRISPR/Cas9 gene editing
Transcriptome sequencing of HELZ-null HEK293T human cell line generated by CRISPR/Cas9 gene editing
PRJNA559139 | ENA
GenomicsHELZ promotes R loop resolution to facilitate DNA double-strand break repair by homologous recombination
HELZ promotes R loop resolution to facilitate DNA double-strand break repair by homologous recombination
PRJNA1013807 | ENA
TranscriptomicsTranscriptome sequencing of HELZ-null HEK293T human cell line generated by CRISPR/Cas9 gene editing
Eukaryotic SF1 helicases have been implicated in various aspects of RNA metabolism, including transcription, processing, translation, and degradation. Nevertheless, until now most human SF1 helicases remain poorly understood. Here, we have functionally and biochemically characterized the role of a p...
ORGANISM(S): Homo sapiens 
2019-09-17 | GSE135505 | GEO
GenomicsHELZ promotes R loop resolution to facilitate DNA double-strand break repair by homologous recombination
Successful R-loop homeostasis consists of its timely biogenesis and removal throughout the genome to regulate diverse cellular processes. Yet, they are considered hazardous source to our genome when their turnover goes awry. Here, we report HELZ, a novel player in R-loop homeostasis and DNA repair p...
ORGANISM(S): Homo sapiens 
2023-11-01 | GSE242527 | GEO
UnknownHELZ directly interacts with CCR4-NOT and causes decay of bound mRNAs.
Not available
S-EPMC6769256 | biostudies-literature
UnknownThe putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation.
Not available
S-EPMC3135610 | biostudies-literature
UnknownActivity of zero-valent sulfur in sulfidic natural waters.
Not available
S-EPMC4631721 | biostudies-literature
UnknownIdentification of a De Novo Deletion by Using A-CGH Involving PLNAX2: An Interesting Candidate Gene in Psychomotor Developmental Delay.
Not available
S-EPMC9031640 | biostudies-literature
UnknownLeveraging genome characteristics to improve gene discovery for putamen subcortical brain structure.
Not available
S-EPMC5691156 | biostudies-literature
Sort   by:  
 Page size