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ProteomicsHypothalamic Proteomics analysis of lipopolysaccharide (LPS)-induced depressed mice
Hypothalamic dysfunction is a key pathological factor in inflammation-associated depression. In the present study, isobaric tags for relative-absolute quantitation (iTRAQ) combined with mass spectrometry were employed to detect the proteomes in the hypothalamus of the lipopolysaccharide (LPS)-induce...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-09 | PXD016040 | Pride
Depression Hypothalamus Lipopolysaccharide Itraq lc-ms/ms Brain tissue 
ProteomicsTemporal proteomics characterization of COVID-19 patient sera
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
PXD035471 |
ProteomicsTurboID-based proximity labeling identifies reticulon-like protein B2 as a pro-viral factor coopted for the biogenesis of viral replication organelles in plants
Although intensive studies have been performed to identify and characterize host factors involved in viral replication complex formation, the high dynamism of this process and the insoluble properties of the complex make it difficult to be analyzed comprehensively using traditional affinity purifica...
ORGANISM(S): Nicotiana Benthamiana 
2023-02-12 | PXD040073 |
ProteomicsLow Dose Radiation Induces New Protein Synthesis that Promotes Cancer Radiotherapy Resistance
Radiotherapy (RT) is a cornerstone of cancer treatment; however, its efficacy is frequently hampered by its adverse effects on normal tissues. By studying the effects of high-dose radiotherapy (HDRT) and low-dose radiotherapy (LDRT), we found that cancer cells adapt distinct responses to these doses...
ORGANISM(S): Homo Sapiens 
2026-02-26 | PXD074928 |
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