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Pediatric acute lymphoblastic leukemia (ALL) contains cytogenetically distinct subtypes that respond differently to cytotoxic drugs. Subtype classification can be also achieved through gene expression profiling. However, how to apply such classifiers to a single patient and correctly diagnose the di...
ORGANISM(S): Homo sapiens 
Here, we report a simple, rapid, and practical approach of mass-adaptive coating-assisted single-cell proteomics (Mad-CASP). Combined with the designed synthetic peptides and novel data acquisition strategy, 1240 ± 93 (n = 3) proteins were identified from a single HeLa cell by Mad-CASP.
ORGANISM(S): Homo Sapiens 
2023-10-17 | PXD046177 |
This study combined co-immunoprecipitation (Co-IP) and LC-MS/MS proteomics in MARCH8-overexpressing HeLa cells to identify potential substrates of the E3 ubiquitin ligase MARCH8. Using empty vector-transfected cells as controls, we generated a comprehensive protein interaction dataset to elucidate M...
ORGANISM(S): Homo Sapiens 
2025-03-23 | PXD062157 |
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