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ProteomicsIntegrative Proteomics and Phosphoproteomics Profiling Reveals Molecular Pathways in hypoxia adaptation of brain tissue in Lasiopodomys brandtii
Exposure to high-altitude hypoxic environments may lead to dysfunction in the central nervous system. Research on the hypoxic response mechanisms of hypoxia-tolerant animals can provide insights for animal conservation and the treatment of ischemic brain injury. In this study, we focused on Brandt's...
ORGANISM(S): Lasiopodomys Brandtii 
2024-10-17 | PXD056880 |
ProteomicsLabel-free serum proteome in the rabbit CAS provocation model
A rabbit CAS provocation model was established to screen potential diagnostic biomarkers using quantitative serum proteomics
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-29 | PXD036383 |
ProteomicsFunctional Optic Tract Rewiring via Subtype- and Target-specific Axonal Regeneration and Presynaptic Activity Enhancement
We showed that with genetic manipulation as Pten/Socs3 knockout (KO), CNTF overexpression and Lipin1 knockdown (PSCL), RGCs could regenerate and reinnervate into OPN nuclei after pre-OPN optic tract injury. We then performed single-cell RNA sequencing on OPN-projecting retinal ganglion cells and pro...
ORGANISM(S): Mus Musculus 
2024-05-25 | PXD052573 |
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