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A combinatorial approach to uncover a novel Integrator subunit [RNA-seq]
A combinatorial approach to uncover a novel Integrator subunit [ChIP-seq II]
A combinatorial approach to uncover a novel Integrator subunit [ChIP-seq I]
A combinatorial approach to uncover a novel Integrator subunit
This SuperSeries is composed of the following subset Series: GSE37403: Genome-wide analysis of the SNAPc complex [ChIP-Seq] GSE41528: Genome-wide analysis of the SNAPc complex [Illumina array] Refer to individual Series
ORGANISM(S): Homo sapiens 
The small nuclear RNA (snRNA)-activating protein complex (SNAPc) is a basal transcription factor that mediates the transcriptional activation of snRNAs. Here, we describe the genome-wide occupancy of the SNAPC1_and SNAPC4 subunits of SNAPc. While the SNAPC4 occupancy was in accord with the role for ...
ORGANISM(S): Homo sapiens 
The small nuclear RNA (snRNA)-activating protein complex (SNAPc) is a basal transcription factor that mediates the transcriptional activation of snRNAs. Here, we describe the genome-wide occupancy of the SNAPC1 and SNAPC4 subunits of SNAPc. While the SNAPC4 occupancy was in accord with the role for ...
ORGANISM(S): Homo sapiens 
In this study, we discovered that CDK9-mediated, RNAPII-driven transcription is functionally opposed by a protein phosphatase 2A (PP2A) complex that is recruited to transcription sites by the Integrator complex subunit INTS6. PP2A dynamically antagonises phosphorylation of key CDK9 substrates includ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD025060 | Pride
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