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GenomicsGenome wide mapping of histone acetyltransferase MOF binding in murine ES cells (sequencing)
We report the application of illumina sequencing technology for high-throughput profiling of histone acetyltransferase Mof in mouse embryonic stem cells. By obtaining over four billion bases of sequence from chromatin immunoprecipitated DNA, we generated genome-wide chromatin-state maps of mouse emb...
ORGANISM(S): Mus musculus 
2012-08-09 | E-GEOD-37268 | biostudies-arrayexpress
TranscriptomicsGene expression Microarray analysis for HEK293 WT and ELL KD with control and 1hr EGF stimulated conditions.
Transcription is a multi-stage process that coordinates several steps within the transcription cycle including chromatin reorganization, RNA polymerase II recruitment, initiation, promoter clearance and elongation. Recent advances have identified the super elongation complex (SEC), containing the e...
ORGANISM(S): Homo sapiens 
2011-12-09 | E-GEOD-34104 | biostudies-arrayexpress
TranscriptomicsDetection of Bacillus anthracis DNA in complex soil and air samples using next-generation sequencing [NimbleGen Array data]
One of the cornerstones of an effective biodefense strategy is the ability to detect infectious agents with a high degree of sensitivity and specificity in the context of a complex sample background. The nature of the B. anthracis genome, however, renders specific detection difficult, due to close ...
ORGANISM(S): Bacillus anthracis str. Ames 
2013-06-27 | E-GEOD-48316 | biostudies-arrayexpress
TranscriptomicsDetection of virulence and antibiotic resistance gene families
Emerging known and unknown pathogens create profound threats to public health. Platforms for rapid detection and characterization of microbial agents are critically needed to prevent and respond to disease outbreaks. Available detection technologies cannot provide broad functional information about ...
ORGANISM(S): Staphylococcus aureus subsp. aureus Mu50 
2008-04-02 | E-GEOD-11010 | biostudies-arrayexpress
GenomicsGenome-wide maps of CtBP binding profile in breast cancer cell line MCF-7
CtBP is a global co-repressor by serving as transcriptional factor in multiple pathways. CtBP functioned as transcriptional factor by recruiting other cofactors such as G9a, HDAC1 and PcG proteins. CtBP is found to be over enriched in several type of tumor samples. To dipict the role of CtBP in glob...
ORGANISM(S): Homo sapiens 
2013-03-20 | E-GEOD-36546 | biostudies-arrayexpress
TranscriptomicsGlobal mRNA gene expression analysis profiling control HEK293 cell and cells expressing HSP70K71E
This is global mRNA gene expression data for HEK293 and cells expressing HSP70K71E ; most genes were down-regulated for HSP70K71E compared to the control Keywords: Global mRNA expression We overexpressed pCI1-EGFP (control) and Hsp70K71E-EGFP to HEK293 and collected total RNA from each condition t...
ORGANISM(S): Homo sapiens 
2013-09-24 | E-GEOD-50547 | biostudies-arrayexpress
TranscriptomicsExpression data from CtBP knockdown MCF-7 cells
CtBP is a global co-repressor by serving as transcriptional factor in multiple pathways. CtBP functioned as transcriptional factor by recruiting other cofactors such as G9a, HDAC1 and PcG proteins. CtBP is found to be over enriched in several type of tumor samples. To dipict the role of CtBP in glob...
ORGANISM(S): Homo sapiens 
2013-03-20 | E-GEOD-36529 | biostudies-arrayexpress
GenomicsGlobal transcriptional role of CtBP in breast cancer cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-03-20 | E-GEOD-36598 | biostudies-arrayexpress
TranscriptomicsThe Microbial Detection Array Combined with Random Phi29-Amplification used as a Diagnostic Tool for Unbiased Virus Detection in Clinical Samples
A common technique used for sensitive and specific diagnostic virus detection in clinical samples is PCR. However, an unbiased diagnostic microarray containing probes for all human pathogens could replace hundreds of individual PCR-reactions and remove the need for a clear clinical hypothesis regard...
ORGANISM(S): Homo sapiens 
2011-04-14 | E-GEOD-28597 | biostudies-arrayexpress
TranscriptomicsValidation data for Lawrence Livermore Microbial Detection Array version 2
We designed a pan-Microbial Detection Array (MDA) to detect all known viruses (including phage), bacteria, and plasmids. Family-specific probes were selected for all sequenced viral and bacterial complete genomes, segments, and plasmids. Probes were designed to tolerate some sequence variation to en...
ORGANISM(S): Bovine viral diarrhea virus 1 
2010-10-15 | E-GEOD-24626 | biostudies-arrayexpress
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