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MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
ProteomicsPROTEOMIC ANALYSIS OF THE UMBILICAL CORD IN FETAL GROWTH RESTRICTION AND PREECLAMPSIA
Fetal growth restriction (FGR) is associated with adverse perinatal outcomes. Pre-eclampsia (PreE) increases the associated perinatal morbidity and mortality. The structure of the umbilical cord in the setting of FGR and PreE has yet to be determined. This study aimed to examine chan...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-15 | MSV000087051 | MassIVE
ProteomicsProteomic Analysis of Arylamine N-Acetyltransferase 1 Knockout Breast Cancer Cells
Description A phase II metabolic enzyme, NAT1 is frequently upregulated in breast cancers. Previous studies have shown that inhibition or depletion of NAT1 in breast cancer cell lines leads to growth retardation both in vitro and in vivo, suggesting that NAT1 contributes to rapid growth of breast ca...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035953 | Pride
Breast cancer Nat1 Mda Tmt10plex 
ProteomicsBottom-up proteomics of EZH2 mutants in isogenic cells
The Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit (EZH2) is an essential epigenetic modifier able to methylate lysine 27 on histone H3 (H3K27) to induce chromatin compaction, protein complex recruitment and ultimately transcriptional repression. Hematologic malignancies, including Diffus...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042875 | Pride
Lymphoma Epigenetics Leukemia Mutations Ezh2 
UnknownProtection against SARS-CoV-2 Omicron BA.1 variant challenge in macaques by prime-boost vaccination with Ad26.COV2.S and SpFN.
Not available
S-EPMC9683731 | biostudies-literature
UnknownManagement of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline.
Not available
S-EPMC6481621 | biostudies-literature
TranscriptomicsTranscription profiling of yeast treated with rapamycin, time series
Not available
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-02 | E-MAXD-4 | biostudies-arrayexpress
UnknownInfection- and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant.
Not available
S-EPMC7980225 | biostudies-literature
UnknownClinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.
Not available
S-EPMC10618742 | biostudies-literature
UnknownThe Integrated Genomic Landscape of Thymic Epithelial Tumors.
Not available
S-EPMC5994906 | biostudies-literature
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