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TranscriptomicsTranscription profiling of Dahl salt-sensitive and salt-resistant congenic rats
Kidney samples from three Dahl Salt-sensitive S rats were compared with kidney samples from three S.R(9)x3A congenic rats.
ORGANISM(S): Rattus norvegicus 
2007-09-13 | E-GEOD-1775 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Hela cells treated with the topoisomerase poison camptothecin
Pharmacogenomic identification of targets for adjuvant therapy with the topoisomerase poison camptothecin. The response of tumor cells to the unusual form of DNA damage caused by topoisomerase poisons such as camptothecin (CPT) is poorly understood, and knowledge regarding which drugs can be effecti...
ORGANISM(S): Homo sapiens 
2007-07-29 | E-GEOD-1417 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fat samples from gastric bypass patients
Fat tissue was resected during gastric bypass surgery for management of obesity. All subjects had fasted at least 10 hours before surgery. Subjects with malignancies were excluded. No subjects were taking thiazolidinediones or steroids. None had fasting plasma glucose levels over 120 mg/ dl. One ha...
ORGANISM(S): Homo sapiens 
2007-11-11 | E-GEOD-1657 | biostudies-arrayexpress
UnknownFirst-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer.
Not available
S-EPMC5648176 | biostudies-literature
TranscriptomicsGene Expression of Kidney from FHH and Nr4a1 Deficient Rats
Nr4a1 deficient rats (Nr4a1-/-) were developed using the fawn hooded hypertensive rat (FHH), which provided a genetic background susceptible to kidney injury. Both groups of animals were evaluated for blood pressure, proteinuria, renal function, and whole transcriptome gene pathway changes. Gene exp...
ORGANISM(S): Rattus norvegicus 
2014-02-06 | E-GEOD-54714 | biostudies-arrayexpress
GenomicsSetDB1 Contributes to Repression of Genes Encoding Developmental Regulators and Maintenance of ES Cell State
Transcription factors that play key roles in regulating embryonic stem (ES) cell state have been identified, but the chromatin regulators that help maintain ES cells are less well understood. A high-throughput shRNA screen was used to identify novel chromatin regulators that influence ES cell state...
ORGANISM(S): Mus musculus 
2009-11-01 | E-GEOD-18371 | biostudies-arrayexpress
UnknownMulticenter Phase IB Trial of Carboxyamidotriazole Orotate and Temozolomide for Recurrent and Newly Diagnosed Glioblastoma and Other Anaplastic Gliomas.
Not available
S-EPMC5993168 | biostudies-literature
UnknownPilot studies for development of an HIV subtype panel for surveillance of global diversity.
Not available
S-EPMC3358106 | biostudies-literature
GenomicsMutant p53 cooperates with ETS2 to promote etoposide resistance [ChIP-Seq]
Mutant p53 (mtp53) promotes chemotherapy resistance through multiple mechanisms including disabling pro-apoptotic proteins and by regulating gene expression. Analysis of promoter regions identified through CHIP-on-CHIP and CHIP-SEQ platforms reveal that the ETS motif (EBS) is prevalent within predic...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-36749 | biostudies-arrayexpress
TranscriptomicsMutant p53 cooperates with ETS2 to promote etoposide resistance [ChIP-chip]
Mutant p53 (mtp53) promotes chemotherapy resistance through multiple mechanisms including disabling pro-apoptotic proteins and by regulating gene expression. Analysis of promoter regions identified through CHIP-on-CHIP and CHIP-SEQ platforms reveal that the ETS motif (EBS) is prevalent within predic...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-36751 | biostudies-arrayexpress
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