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TranscriptomicsEarly-induced genes of human regulatory CD4+CD25hi Treg and CD4+CD25- Th cells
Goals and objectives of this study: to identify genes preferentially induced in human CD4+CD25hi Treg cells following T-cell activation with potential role for stabililization & maintenance of the regulatory program. Keywords: T-cell receptor stimulation, gene-regulation, comparative gene expressio...
ORGANISM(S): Homo sapiens 
2009-04-20 | E-GEOD-13017 | biostudies-arrayexpress
TranscriptomicsHuman activated Treg cells and retrovirally engineered Th cells, transduced with GARP, FOXP3 or control GFP vector
Goals and objectives of this study: to identify genes of the Treg signature induced by consitutive expression of GARP or FOXP3 in antigen-specific Th cells with potential role for stabililization & maintenance of the regulatory program. Keywords: T-cell receptor stimulation, gene-regulation, compar...
ORGANISM(S): Homo sapiens 
2009-04-20 | E-GEOD-13234 | biostudies-arrayexpress
UnknownGARP: a key receptor controlling FOXP3 in human regulatory T cells.
Not available
S-EPMC4516490 | biostudies-literature
TranscriptomicsTranscription profiling of human Th cells expressing Foxp3 and UBD ectopically
Expression analysis revealed that UBD is a down-stream element of Foxp3 in human activated regulatory CD4+ T cells (Treg). Experiment Overall Design: Comparison of expression profiles measured in naturally occuring regulatory T-cells (Treg), Foxp3 and UBD transformed Th cells versus their controls w...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4527 | biostudies-arrayexpress
UnknownSemi-Quantitative Multiplex Profiling of the Complement System Identifies Associations of Complement Proteins with Genetic Variants and Metabolites in Age-Related Macular Degeneration.
Not available
S-EPMC8705464 | biostudies-literature
UnknownSystematical assessment of the impact of single spike mutations of SARS-CoV-2 Omicron sub-variants on the neutralization capacity of post-vaccination sera.
Not available
S-EPMC10667444 | biostudies-literature
UnknownProteome analysis of distinct developmental stages of human natural killer (NK) cells.
Not available
S-EPMC3650324 | biostudies-literature
TranscriptomicsProfiling of Jurkat T cells activated with CD3, CD28 and PMA at 1 and 8 hours
T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype, depending on environmental co-stimulatory signals. In order to identify the genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes ...
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-30676 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human regulatory T cells to identify genes under Foxp3 control
Foxp3, a transcription factor of the forkhead/winged helix family, plays a unique role in the transcriptional control of regulatory CD4+CD25+ T (Treg) cells. The identification of potential target genes associated with the regulatory phenotype and the characterization of combinatorial interactions o...
ORGANISM(S): Homo sapiens 
2005-01-24 | E-MEXP-228 | biostudies-arrayexpress
TranscriptomicsProfiling of Jurkat T cells activated with CD3, CD28 and PMA and multiple kinase inhibitors
T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype, depending on environmental co-stimulatory signals. In order to identify the genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes ...
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-30674 | biostudies-arrayexpress
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