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ProteomicsThe long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia
In this work we dissect the functional role of the HOXB-AS3 long non coding RNA in patients with NPM1-mutated (NPM1mut) acute myeloid leukemia (AML). We show that HOXB-AS3 regulates the proliferative capacity of NPM1mut AML blasts in vitro and in vivo. HOXB-AS3 was found to interact with the ErbB3-b...
ORGANISM(S): Homo sapiens (Human) 
2019-10-16 | PXD015520 | Pride
Hoxb-as3 Acute myeloid leukemia Lncrna Ebp1 
UnknownFRODOCK: a new approach for fast rotational protein-protein docking.
Not available
S-EPMC2800348 | biostudies-literature
UnknownClinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients.
Not available
S-EPMC3731981 | biostudies-literature
UnknownEpigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score.
Not available
S-EPMC3918538 | biostudies-literature
TranscriptomicsMicroRNA profiling of human chronic lymphocytic leukemia samples to identify whether microRNA profiles are prognostic indicators
MicroRNA expression profiles can distinguish normal B cells from malignant B cells in chronic lymphocytic leukemia (CLL). We investigated whether microRNA profiles are associated with known prognostic factors in CLL. We evaluated the microRNA expression profiles of 94 samples of CLL cells for which ...
ORGANISM(S): Homo sapiens 
2005-10-27 | E-TABM-41 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chronic lymphocytic leukemia miRNA expression validation
MicroRNA expression profiles can distinguish normal B cells from malignant B cells in chronic lymphocytic leukemia (CLL). We investigated whether microRNA profiles are associated with known prognostic factors in CLL. We evaluated the microRNa expression profiles of 94 samples of CLL cells for which ...
ORGANISM(S): Homo sapiens 
2005-10-27 | E-TABM-42 | biostudies-arrayexpress
TranscriptomicsCXCR4/YinYang1/Hsa-let-7a axis functions as tumor suppressor in acute myeloid leukemia
Surface expression of C-X-C chemokine receptor type 4 (CXCR4) in acute myeloid leukemia (AML) has been reported to be an independent prognostic factor for disease relapse and survival. We previously reported that targeting the stromal-derived factor 1M-NM-1 (SDF-1M-NM-1)/CXCR4 axis could overcome re...
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-44828 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human multiple myeloma cells and monoclonal gammopathy of undetermined significance (MGUS) cells
MicroRNA expression profiles for human Multilple Myeloma and MGUS (monoclonal gammopathy of undetermined significance) were examined to investigate the miRNA involvement in the development of this neoplasia.
ORGANISM(S): Homo sapiens 
2008-09-03 | E-TABM-508 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of patients with acute myeloid leukemia to identify microRNA signatures associated with cytogenetics and prognosis
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
ORGANISM(S): Homo sapiens 
2008-01-10 | E-TABM-405 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human acute myeloid leukemia samples from patients characterized for subcellular localization/mutation status of NPM1 and FLT3 mutations
Acute myeloid leukemia (AML) carrying NPM1 mutations and cytoplasmic nucleophosmin (NPMc+ AML) accounts for about one-third of adult AML and shows distinct features, including a unique gene expression profile. MicroRNAs (miRNAs) are small noncoding RNAs of 19-25 nucleotides in length that have been ...
ORGANISM(S): Homo sapiens 
2008-03-14 | E-TABM-429 | biostudies-arrayexpress
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