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TranscriptomicsTranscription profiling of human prostate cancer cell line to determine Ebp1 effect in prostate cancer
Therapies targeting the androgen receptor are critical for treatment of hormone refractory prostate cancer. We have previously demonstrated that Ebp1, a protein isolated by its ability to bind ErbB3, is a downstream effector of heregulin activated pathways and an AR corepressor. As Ebp1 is decreased...
ORGANISM(S): Homo sapiens 
2008-11-13 | E-GEOD-12200 | biostudies-arrayexpress
TranscriptomicsAlterations in Cell Growth and Signaling in ErbB3 Binding Protein -1 (Ebp1) Deficient Mice
Background: The ErbB3 binding protein-1 (Ebp1) belongs to a family of DNA/RNA binding proteins implicated in cell growth, apoptosis and differentiation. However, the physiological role of Ebp1 in the whole organism is not known. Therefore, we generated Ebp1-deficient mice carrying a gene trap insert...
ORGANISM(S): Mus musculus 
2009-03-31 | E-GEOD-13718 | biostudies-arrayexpress
GenomicsEbp1-selective ribosome profiling analysis of Neuro2a cells with Ebp1-immuno-precipitation
Ebp1-selective ribosome profiling analysis of Neuro2a cells with Ebp1-immuno-precipitation
PRJNA661060 | ENA
ProteomicsProtein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit
Proteostasis must be finely tuned in the nervous system, as it represents an essential feature of neurodevelopment, and dominant pathology in neurodegenerative disease. At the gateway of proteostasis is the ribosome; however, the architecture of ribosomal complexes in the developing mammalian brain ...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-04 | PXD014841 | Pride
Development Neocortex Ribosome Ebp1 Proteostasis 
ProteomicsProtein synthesis in the developing neocortex at near-atomic resolution reveals Ebp1-mediated neuronal proteostasis at the 60S tunnel exit
Proteostasis must be finely tuned in the nervous system, as it represents an essential feature of neurodevelopment, and dominant pathology in neurodegenerative disease. At the gateway of proteostasis is the ribosome; however, the architecture of ribosomal complexes in the developing mammalian brain ...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-04 | PXD014740 | Pride
Development Neocortex Ribosome Ebp1 Proteostasis Orbitrap 
GenomicsRibosome profiling analysis of Neuro2a cells with Ebp1 knockdown
Ribosome profiling analysis of Neuro2a cells with Ebp1 knockdown
PRJNA661275 | ENA
TranscriptomicsEbp1-selective ribosome profiling analysis of Neuro2a cells with Ebp1-immuno-precipitation
We perform Selective Ribosome Profiling (SeRP) analysis of mouse Neuro2a neuronal cultures with Ebp1-immuno-precipitation in biological duplicate to assess the translation-specific function of Ebp1
ORGANISM(S): Mus musculus 
2021-03-23 | GSE157361 | GEO
TranscriptomicsEbp1's effect in prostate cancer
Therapies targeting the androgen receptor are critical for treatment of hormone refractory prostate cancer. We have previously demonstrated that Ebp1, a protein isolated by its ability to bind ErbB3, is a downstream effector of heregulin activated pathways and an AR corepressor. As Ebp1 is decreased...
ORGANISM(S): Homo sapiens 
2008-10-31 | GSE12200 | GEO
TranscriptomicsRibosome profiling analysis of Neuro2a cells with Ebp1 knockdown
We perform Ribosome Profiling (Riboseq) analysis of mouse Neuro2a neuronal cultures in Ebp1-siRNA knockdown vs. scrambled-siRNA control conditions in biological triplicate to assess the translation-specific function of Ebp1
ORGANISM(S): Mus musculus 
2021-03-23 | GSE157423 | GEO
TranscriptomicsAlterations in Cell Growth and Signaling in ErbB3 Binding Protein -1 (Ebp1) Deficient Mice
Background: The ErbB3 binding protein-1 (Ebp1) belongs to a family of DNA/RNA binding proteins implicated in cell growth, apoptosis and differentiation. However, the physiological role of Ebp1 in the whole organism is not known. Therefore, we generated Ebp1-deficient mice carrying a gene trap insert...
ORGANISM(S): Mus musculus 
2009-03-31 | GSE13718 | GEO
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