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MetabolomicsShort-term changes in the serum metabolome after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass

INTRODUCTION: Bariatric surgery is known to be the most effective treatment for weight loss in obese patients and for the rapid remission of obesity-related comorbidities. These short-term improvements result from not only limited digestion or absorption but also dynamic changes ...

2022-03-17 | MTBLS2472 | MetaboLights
MetabolomicsA low protein diet drives short and long-term improvements in metabolic health in a mouse model of sleeve gastrectomy

Despite the largely beneficial impact of bariatric surgery on obesity and metabolic disease, many patients continue to suffer from obesity after surgery and weight recurrence is common. The success of bariatric surgery may be impacted by diet. While bariatric surgery guidelines recommend a high-p...

2025-10-13 | MTBLS13046 | MetaboLights
MetabolomicsThe Role of Intestinal-derived FGF15 and Vertical Sleeve Gastrectomy on Plasma Bile Acid Composition in Mice
Not available
ORGANISM(S): Mus musculus 
ST001743 | MetabolomicsWorkbench
TranscriptomicsGene expression profiling of the ileum following vertical sleeve gastrectomy compared to pair-fed sham surgery controls in mice with high-fat diet-induced obesity.
We report the expression profiles of ileal samples extracted from obese male C57Bl6 mice following vertical sleeve gastrectomy or sham surgery, focusing of gene signatures indicative of altered bile acid metabolism. We induced obesity in male C57bl6 mice through a high-fat diet. At 8 weeks, they we...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-53782 | biostudies-arrayexpress
ProteomicsPeptidomics profiling of biopsies from the human jejunum before and after gastrectomy
Profiling of the human jejunum peptidome before and after total gastrectomy. The study compares the peptidome of jejunum using intact mass spectrometry and database searching. These peptides included most gut hormones including proglucagon derived peptides, PYY, GIP, Motilin somatostatin and neurote...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD011498 | Pride
Gastrectomy Jejunum Peptidomics Gut hormones 
MetabolomicsMetabolomic fingerprint of severe obesity is dynamically affected by bariatric surgery in a procedure-dependent manner
Obesity is associated with multiple diseases. Bariatric surgery is the most effective therapy for severe obesity that can reduce body weight and obesity-associated morbidity. The metabolic alterations associated with obesity and respective changes after bariatric surgery are incompletely understood....
2017-02-10 | MTBLS242 | MetaboLights
Genomics
Gastrectomy
PRJNA398791 | ENA
GenomicsTranscriptomics analysis of enteroendocrine cells after vertical sleeve gastrectomy
Transcriptomics analysis of enteroendocrine cells after vertical sleeve gastrectomy
PRJNA497455 | ENA
GenomicsTranscriptomics analysis of human jejunal enteroendocrine cells after vertical sleeve gastrectomy
Transcriptomics analysis of human jejunal enteroendocrine cells after vertical sleeve gastrectomy
PRJNA497450 | ENA
ProteomicsBeaumont/Cornell Health Sleeve Gastrectomy Patient Cohort
Fecal samples from patients undergoing sleeve gastrectomy as a treatment modality for obesity.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-20 | MSV000093167 | MassIVE
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