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Modern pharmacology has proved that Codonopsis Radix and its active ingredients can treat stomach diseases by ameliorating gastrointestinal motility and regulating oxidase levels. However, the detailed molecular mechanism is still unclear. In this study, we systematically evaluated the pharmacodynam...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-10-15 | PXD032714 | Pride
Dissecting Expression Profiles of Gastric Precancerous Lesions and Early Gastric Cancer to Explore Crucial Molecules in Intestinal-type Gastric Cancer Tumorigenesis
Base on the classification of damp syndrome, we classified gastric precancerous lesions patients into distinct subtypes. In this cross-sectional investigation, we aim figure out the clinical feature difference between different subtypes. Furthermore, we conduct multi-omics analyses on blood sample...
ORGANISM(S): Homo Sapiens 
Gastric cancer (GC) is among the most aggressive malignancy affecting the world population. With almost a million cases remains in fifth position in incidence, while reaching the third position in mortality. The progression of GC is slow with several prolonged and sequential precancerous stages, inc...
ORGANISM(S): Homo sapiens (Human) 
2019-09-27 | PXD008081 | Pride
Fragment data of GC,HC,GB in paper titled Circulating Cell-Free mtDNA Fragmentomics for Early Detection of Gastric Cancer and Precancerous Lesions
ORGANISM(S): Homo sapiens 
To identify dysregulated miRNA(s) upon infection with H. pylori during different pre-malignant and malignant stages of gastric cancer in a mouse model miRNA expression in pre-neoplastic and neoplastic lesions in murine stomachs induced by H. pylori and N-methyl-N-nitrosourea (MNU) after 12 months wa...
ORGANISM(S): Mus musculus 
To investigate the changes in molecular expression, biological processes, stemness, immune microenvironment, tumor hallmark activities and co-expression relationships during intestinal-type gastric cancer carcinogenesis and to excavate the prognostic information contained in the carcinogenesis proce...
ORGANISM(S): Homo sapiens 
2020-03-15 | GSE130823 | GEO
To explore the effects of bile reflux on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.
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