Hsp90 constitutes one of the major chaperone machinery in the cell. The Hsp70 assists Hsp90 in its client maturation though the underlying basis of the Hsp70 role remains to be explored. In the present study we identified novel mutations in the nucleotide-binding domain of yeast Ssa1 Hsp70 (Ssa1-T17...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast)