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TranscriptomicsA validated gene regulatory network and GWAS identifies early regulators of T-cell associated diseases
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-11-12 | E-GEOD-60680 | biostudies-arrayexpress
TranscriptomicsA validated gene regulatory network and GWAS identifies early regulators of T-cell associated diseases (Th1 Th2)
In this work we present an analytical strategy to systematically identify early regulators by combining gene regulatory networks (GRN) with GWAS. We hypothesized that early regulators in T-cell associated diseases could be found by defining upstream transcription factors (TFs) in T-cell differentia...
ORGANISM(S): Homo sapiens 
2015-11-12 | E-GEOD-60678 | biostudies-arrayexpress
TranscriptomicsA validated gene regulatory network and GWAS identifies early regulators of T-cell associated diseases [MAF siRNA]
In this work we present an analytical strategy to systematically identify early regulators by combining gene regulatory networks (GRN) with GWAS. We hypothesized that early regulators in T-cell associated diseases could be found by defining upstream transcription factors (TFs) in T-cell differentia...
ORGANISM(S): Homo sapiens 
2015-11-12 | E-GEOD-61964 | biostudies-arrayexpress
TranscriptomicsA validated gene regulatory network and GWAS identifies early regulators of T-cell associated diseases (Th17 Treg)
In this work we present an analytical strategy to systematically identify early regulators by combining gene regulatory networks (GRN) with GWAS. We hypothesized that early regulators in T-cell associated diseases could be found by defining upstream transcription factors (TFs) in T-cell differentia...
ORGANISM(S): Homo sapiens 
2015-11-12 | E-GEOD-60679 | biostudies-arrayexpress
TranscriptomicsA validated gene regulatory network and GWAS identifies early regulators of T-cell associated diseases (exon array)
In this work we present an analytical strategy to systematically identify early regulators by combining gene regulatory networks (GRN) with GWAS. We hypothesized that early regulators in T-cell associated diseases could be found by defining upstream transcription factors (TFs) in T-cell differentia...
ORGANISM(S): Homo sapiens 
2015-11-12 | E-GEOD-60677 | biostudies-arrayexpress
GenomicsA validated gene regulatory network and GWAS identifies early regulators of T-cell associated diseases (ChIP-Seq)
For the purpose of the Gene Regulatory Network validation we have performed chromatin-immunoprecipitation sequencing (ChIP-Seq) experiment for three transcription factors; namely GATA3, MAF and MYB. ChIP-Seq of GATA3, MAF and MYB in human naïve CD4+ T-cells differentiated toward Th1 and Th2 until d...
ORGANISM(S): Homo sapiens 
2015-11-12 | E-GEOD-72266 | biostudies-arrayexpress
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