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to find functional relevance between SMC5/6 complex and SAGA histone acetyltransferase complex in Schizosaccharomyces pombe by chromatin immunoprecipitation of Nse4-FLAG tagged protein from gcn5, ubp8 and ada2 deletion strains and 2 control strains (WT - Nse4-FLAG, 501 - no tag).
ORGANISM(S): Schizosaccharomyces pombe 
During evolution, there has been an expansion in the diversity of histone acetyltransferase Gcn5-containing complexes. All Gcn5 complexes share Sgf29 and Ada3 subunits, which together with their respective Ada2 homolog, enable nucleosomal HAT activity. In metazoans, including Drosophila, there are t...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2017-12-07 | MSV000081791 | MassIVE
Nse4-FLAG CHIP-seq analysis in gcn5, ubp8, ada2 deletion background in S.pombe, control wt 501 - no tag
Histone post-translational modifications (PTMs) are critical for processes such as transcription. The more notable among these are the non-acetyl histone lysine acylation modifications such as crotonylation, butyrylation and succinylation. However, the biological relevance of these PTMs is not fully...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) Xenopus laevis (African clawed frog) 
2019-11-06 | PXD015488 | Pride
The SAGA complex is a highly conserved histone acetyltransferase (HAT) complex in eukaryotes, playing crucial role in regulating gene transcription throughout organismal development. The complex consists of two core components: GCN5, the HAT subunit, and ADA2, which primarily functions as an adaptor...
ORGANISM(S): Oryza sativa Japonica Group 
2025-09-23 | GSE300491 | GEO
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