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ProteomicsThe role of the sRNA GcvB in Pasteurella multocida protein production
In this study, transcriptomic analysis of the P. multocida strain VP161 revealed a putative sRNA with high identity to GcvB from Escherichia coli and Salmonella enterica serovar Typhimurium. High-throughput quantitative liquid proteomics was used to compare the proteomes of the P. multocida VP161 wi...
ORGANISM(S): Pasteurella multocida 
2019-11-12 | PXD007719 | Pride
Lc-ms/ms Pasteurella multocida Gcvb 
TranscriptomicsRNA-Seq samples of E. coli K12 MG1655, deletion of gcvB sRNA gene, temperature mutation in RNAse E.
Small RNAs (sRNAs) are major regulators of gene expression in bacteria. Traditionally, sRNAs were considered mainly as regulators of translation, exerting their regulatory function by base pairing with their target mRNAs, and through this, blocking or exposing the ribosome binding site. However, acc...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2024-05-12 | E-MTAB-12466 | biostudies-arrayexpress
TranscriptomicsRNA-seq data of Escheirchia coli K12 MG1655 of overexpression of GcvB, MicA, ArcZ, RyhB or CyaR sRNAs
To study the regulatory outcome of Hfq-mediated sRNA-target interactions, we measured the change in gene expression following overexpression of each of five well-established sRNAs: GcvB, MicA, ArcZ, RyhB and CyaR. For each of the studied sRNAs we applied RNA-seq to two E. coli K-12 MG1655 strains: (...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2020-03-03 | E-MTAB-8229 | biostudies-arrayexpress
UnknownDetermination of the small RNA GcvB regulon in the Gram-negative bacterial pathogen Pasteurella multocida and identification of the GcvB seed binding region.
Not available
S-EPMC5900567 | biostudies-literature
GenomicsSmall RNA GcvB regulates oxidative stress response of Escherichia coli through its control of OxyR
Small RNA GcvB regulates oxidative stress response of Escherichia coli through its control of OxyR
PRJNA756678 | ENA
UnknownSmall RNA GcvB Regulates Oxidative Stress Response of Escherichia coli.
Not available
S-EPMC8614746 | biostudies-literature
TranscriptomicsGlobal post-transcriptional control of genes involved in amino acid metabolism by the Hfq-dependent GcvB RNA
The control of amino acid synthesis and transport in bacteria has been well-investigated at the transcriptional level. The discovery of a small Hfq-dependent regulatory RNA, GcvB, added another layer of gene expression control at the post-transcriptional level. GcvB RNA has been shown to directly re...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2011-07-01 | GSE26573 | GEO
UnknownGcvB Regulon Revealed by Transcriptomic and Proteomic Analysis in Vibrio alginolyticus.
Not available
S-EPMC9409037 | biostudies-literature
TranscriptomicsSmall RNA GcvB regulates oxidative stress response of Escherichia coli through its control of OxyR
We investigated the gene expression changed in the NCM3722 wild-type and gcvB deletion strains grown in glucose minimal medium, aiming to find novel target genes controlled by small RNA GcvB. In total, five differentially expressed genes (DEGs) were identified by Illumina sequencing using a cutoff w...
ORGANISM(S): Escherichia coli 
2021-12-09 | GSE182531 | GEO
GenomicsRNA-Seq samples of E. coli K12 MG1655, deletion of gcvB sRNA gene, temperature mutation in RNAse E.
RNA-Seq samples of E. coli K12 MG1655, deletion of gcvB sRNA gene, temperature mutation in RNAse E.
PRJEB58300 | ENA
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