Sort   by:  
 Page size 
GenomicsFunctional association of Gdown1 with RNA Polymerase II in Human
Most human genes are loaded with promoter proximally paused RNA polymerase II (RNAP II) molecules that are poised for release into productive elongation by P-TEFb. Gdown1, a protein that renders RNAP II responsive to mediator, is involved in RNAP II elongation control. During in vitro transcription ...
ORGANISM(S): Homo sapiens 
2012-01-13 | E-GEOD-32442 | biostudies-arrayexpress
ProteomicsCharacterization of GFP-Gdown1 interactors by IP and LC-MS/MS
Approximately half of purified mammalian RNA polymerase II (Pol II) is associated with a tightly interacting sub-stoichiometric subunit, Gdown1. Previous studies have established that Gdown1 inhibits transcription initiation through competitive interactions with general transcription factors and blo...
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD029425 | Pride
Gfp Human Ip Gdown1 
GenomicsWhole Cell Extract
Most human genes are loaded with promoter proximally paused RNA polymerase II (RNAP II) molecules that are poised for release into productive elongation by P-TEFb. Gdown1, a protein that renders RNAP II responsive to mediator, is involved in RNAP II elongation control. During in vitro transcription ...
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-35882 | biostudies-arrayexpress
GenomicsRegulation of Mediator-dependent transcriptional activation of Pol II(G) through TFII
Pol II(G) is a novel form of RNA polymerase II that contains a tightly associated Gdown1 polypeptide. Whereas Pol II suffices for robust activator-dependent transcription in the absence of Mediator, Pol II(G) is highly dependent upon Mediator in a biochemically defined in vitro system. However, the ...
ORGANISM(S): Homo sapiens 
2012-01-13 | E-GEOD-33128 | biostudies-arrayexpress
GenomicsDifferentially expressed genes in Gdown1 knockout and Gdown1/p53 double-knockout mouse liver [RNA-seq]
Differentially expressed genes in Gdown1 knockout and Gdown1/p53 double-knockout mouse liver [RNA-seq]
PRJNA603066 | ENA
GenomicsNuclear export restricts Gdown1 to a mitotic function
Nuclear export restricts Gdown1 to a mitotic function
PRJNA772715 | ENA
GenomicsDifferentially expressed genes in Gdown1 KO liver [array]
Differentially expressed genes in Gdown1 KO liver [array]
PRJNA603067 | ENA
UnknownNuclear export restricts Gdown1 to a mitotic function.
Not available
S-EPMC8887472 | biostudies-literature
TranscriptomicsDifferentially expressed genes in Gdown1 knockout and Gdown1/p53 double-knockout mouse liver [RNA-seq]
To investigate the biological role of Gdown1, differentially expressed genes in Gdown1 knockout and p53/Gdown1 double-knockout mouse liver were analyzed by RNA-seq.
ORGANISM(S): Mus musculus 
2021-01-06 | GSE144210 | GEO
TranscriptomicsDifferentially expressed genes in Gdown1 KO liver [array]
To investigate the biological role of Gdown1, we chose mouse liver and generated Gdown1 conditional knockout mice. Differentially expressed genes in Gdown1 KO liver were analyzed by microarrays.
ORGANISM(S): Mus musculus 
2021-01-06 | GSE144209 | GEO
Sort   by:  
 Page size