Sort   by:  
 Page size 
ProteomicsMycobacterium tuberculosis produces D-serine under hypoxia to limit CD8+ T cell-dependent immunity in mice
Interferon (IFN)-γ-producing CD8+ T cells are involved in control of Mycobacterium tuberculosis (Mtb) infection, in part by promoting antimicrobial activities of macrophages. Whether Mtb counters these responses, particularly during the hypoxic conditions that arise within granulomas during infectio...
ORGANISM(S): Mycobacterium tuberculosis OFXR-32 
2024-08-10 | PXD050258 | Pride
Mycobacterium tuberculosis  d-serine  rv0884c  wdr24  mtorc1  cd8+ t cell 
ProteomicsLysine acetylation of DosR regulates the hypoxia response of Mycobacterium tuberculosis
Tuberculosis caused by Mycobacterium tuberculosis (Mtb) infection remains a huge global public health problem. One striking characteristic of Mtb is its ability to adapt to hypoxia, and thus ensuing transition to dormant state for persistent infection, but how the hypoxia responses of Mtb is regulat...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-10-22 | PXD008587 | Pride
Lysine acetylation  mtb dosr  hypoxia growth dna binding 
ProteomicsTAK1 is an essential kinase for STING trafficking
STING-mediated activation of TAK1 at the ER, which in turn induces STING phosphorylation and initiates STEEP-mediated STING trafficking. These findings shed light on an early signaling event in the regulation of STING exit from ER.
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-09-05 | PXD045096 |
Sort   by:  
 Page size