This dataset contains the in vivo turnover rate information of ~3,000 proteins from the mouse heart. Data from six common laboratory mouse strains with differential responses to isoproterenol are included
Doxorubicin is a wildly used effective anticancer agent. However, doxorubicin use is also related to cardiotoxic side effect in some patients. Mitochondrial damage has been shown to be one of the pathogeneses of doxorubicin-induced myocardial injury. In this study, we test the hypothesis that mitoch...
This file include 9 sample: heart sample from WT mice (1, 2, 3)+heart sample from WT mice treated with DOX (4,5,6)+heart sample from HINT2 cKO mice treated with DOX (7,8,9))
To unravel the direct mechanism of the anti-inflammatory effects of IGFBP6 in ECs, we analysed HUVECs treated with either adenovirus-Flag-IGFBP6 (Ad-IGFBP6) or control adenovirus (Ad-NC). We precipitated IGFBP6 from overexpressed ECs followed by mass spectrometry.