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UnknownEfficacy and safety of Xiangsha Liujunzi granules for functional dyspepsia: A multi-center randomized double-blind placebo-controlled clinical study.
Not available
S-EPMC5558122 | biostudies-literature
Proteomicsstreptococcus suis LC-MS/MS - MnmE, a Central tRNA-Modifying GTPase, Is Essential for the Growth, Pathogenicity, and Arginine Metabolism of Streptococcus suis Serotype 2
Streptococcus suis is an important pathogen in pigs and can also cause severe infections in humans. However, little is known about proteins associated with cell growth and virulence of S. suis. In this study, a GTPase MnmE homologue was identified in a Chinese isolate (SC19) that drives a tRNA modif...
ORGANISM(S): Streptococcus suis SC149 
2019-11-13 | PXD012716 | Pride
Ss2 Tmt Mnme 
ProteomicsI.e. mouse ovary palmitoylation protein LC-MSMS
To identify a role for protein palmitoylation in ovarian of DHEA-induced PCOS mice model. First, we used DHEA to induce a PCOS mice model，hematoxylin-eosin (H&E) staining sections form the ovaries of the Control and DHEA groups.The mice oral gavage with DHEA disrupted ovarian morphology,the estrous ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD028835 | Pride
I.e. mouse ovary， palmitoylation protein， lc-msms 
TranscriptomicsEffect of GW4064 on primary cultured mouse kidney proximal tubule cells
Global gene expression in the primary cultured mouse kidney proximal tubule cells treated either DMSO or 1uM GW4064 (a FXR agonist) was compared. Results provide insight into mechanisms underlying effects of FXR activation on gene expression in mouse kidney proximal tubule cells. Male C57/BJ mice ag...
ORGANISM(S): Mus musculus 
2015-06-26 | E-GEOD-70296 | biostudies-arrayexpress
ProteomicsTFIP11 competes with the Bloom syndrome helicase for binding to stalled replication forks to preserve genome stability
Replication fork reversal is a key protective mechanism against replication stress in higher eukaryotic cells and occurs via a series of coordinated enzymatic reactions. The Bloom syndrome gene product, BLM, is a member of the highly conserved RecQ helicase family and has been implicated in this pro...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD042222 | Pride
Bloom syndrome helicase  replication stress  replication fork reversal  genome instability  tfip11 
UnknownGenomic variation associated with local adaptation of weedy rice during de-domestication.
Not available
S-EPMC5477509 | biostudies-literature
TranscriptomicsHSC-3 cells (control) vs. HSC-3-5 cells [subcutaneous tumor]
HSC-3-5 cells, which drived from human HSC-3 cells via transwell invasion assay was high invasive.Tumor cells were injected into the flank of SCID mice. After 6 weeks, transcriptional profiling of human HSC-3 tumor comparing with high invasive HSC-3-5 tumor. Goal was to determine the effects of inv...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-39726 | biostudies-arrayexpress
TranscriptomicsHSC-3 cells (control) vs. HSC-3-5 cells [tongue]
HSC-3-5 cells, which drived from human HSC-3 cells via transwell invasion assay was high invasive.Tumor cells were injected into the tongue of SCID mice. After 1 week, transcriptional profiling of human HSC-3 tumor comparing with high invasive HSC-3-5 tumor. Goal was to determine the effects of inv...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-39725 | biostudies-arrayexpress
TranscriptomicsHSC-3 cells (control) vs. HSC-3-5 cells [cell line]
HSC-3-5 cells were derived from human HSC-3 cells via transwell invasion assay. Transcriptional profiling of human HSC-3 cells comparing with high invasive HSC-3-5 cells. Goal was to determine the effects of invasion on global HSC-3-5 gene expression during tumor metastasis. Two-condition experimen...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-39723 | biostudies-arrayexpress
UnknownNumb positively regulates Hedgehog signaling at the ciliary pocket.
Not available
S-EPMC11045789 | biostudies-literature
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