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TranscriptomicsTranscription profiling of human NSCLC cell lines treated with Trichostatin A and vorinostat to test Anti-tumor Activity of Histone Deacetylase Inhibitors
In order to ascertain the potential for histone deacetylase (HDAC) inhibitor-based treatment in non-small cell lung cancer (NSCLC), we analyzed the anti-tumour effects of Trichostatin A (TSA) and suberoylanilide hydroxamic acid (vorinostat) in a panel of 16 NSCLC cell lines via MTT assay. TSA and v...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10089 | biostudies-arrayexpress
UnknownTranscription profiling of human NSCLC cell lines treated with Trichostatin A and vorinostat to test Anti-tumor Activity of Histone Deacetylase Inhibitors
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-10089 | biostudies-other
TranscriptomicsTranscription profiling of human lung cancer cell lines
Anticancer drug clustering in lung cancer based on gene expression profiles. We performed gene expression analysis in lung cancer cell lines. (used: Affymetrix GeneChip Human Genome U133 Array Set HG-U133A). We also examines the sensitivity of these cell lines to commonly used anti-cancer agents (do...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-4127 | biostudies-arrayexpress
TranscriptomicsMiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer from never-smokers
Approximately 15% of lung cancer cases are not associated with smoking and show molecular and clinical characteristics distinct from those in smokers. Epidermal growth factor receptor (EGFR) gene mutations, which are correlated with sensitivity to EGFR-tyrosine kinase inhibitors (EGFR-TKIs), are mo...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-14936 | biostudies-arrayexpress
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