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MetabolomicsAnalysis of the human adult urinary metabolome variations with age, body mass index and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. ('Sacurine' data set)

Urine metabolomics is widely used for biomarker research in the fields of medicine and toxicology. As a consequence, characterization of the variations of the urine metabolome under basal conditions becomes critical in order to avoid confounding effects in cohort studies. Such physiological infor...

2017-01-20 | MTBLS404 | MetaboLights
MetabolomicsComparison of intestinal microbes and metabolites in active VKH versus acute anterior uveitis associated with ankylosing spondylitis

BACKGROUND: It has been reported that the gut microbiome is involved in the pathogenesis of uveitis, but the specific pathogenic microbes and metabolites in different types of uveitis are still unclear.

METHODS:&...

2023-12-12 | MTBLS7936 | MetaboLights
TranscriptomicsTranscription profiling of post-mortem human brain to investigate gender specific gene expression
Gender differences in brain development and in the prevalence of neuropsychiatric disorders such as depression have been reported. Gender differences in human brain might be related to patterns of gene expression. Microarray technology is one useful method for investigation of gene expression in bra...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2164 | biostudies-arrayexpress
MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Targeted lipidomics analysis of Human Plasma samples and comparison with NIST SRM 1950 standard

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1375 | MetaboLights
ProteomicsGender- and Age-Based Characterization and Comparison of the Murine Primary Peritoneal Mesothelial Cell Proteome
Raw and processed data in support of manuscript "Gender- and Age-Based Characterization and Comparison of the Murine Primary Peritoneal Mesothelial Cell Proteome" Zhikun Wang1,2, Yueying Liu1,2, Reihaneh Safavisohi1,2, Marwa Asem1,2, Daniel Hu1, Mary Sharon Stack1,2,3, Matthew M. Champion1,3 1Depa...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-06-09 | MSV000092134 | MassIVE
MetabolomicsQuick Comparison of Serum Metabolites in SD Rats of Different Sex by Untargeted UPLC-TOFMS and In-house Software Platform
Not available
ORGANISM(S): Rattus norvegicus 
ST000237 | MetabolomicsWorkbench
ProteomicsCommon, Unique and Systemic Signatures in gender-dependent hepatic tumorigenesis: a TMT-based quantitative proteomic analysis
Hepatocellular carcinoma (HCC) is the most common liver cancer and a highly malignant tumor. The frequent activation of Ras signaling pathway and the male prevalence are the distinct characteristics of HCC though the underlying mechanisms remain elucidated. By exploring a mouse model of HCC induced ...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD012410 | Pride
Hepatocellular carcinoma  gender disparity  ras oncogene  proteomics  tandem-mass-tag (tmt) 
TranscriptomicsSexual Dimorphic Regulation of Liver Gene Expression by Glucocorticoids
Males and females exhibit differences in the incidence of many major diseases including auto-immune diseases, hepatocellular carcinoma, diabetes, and osteoporosis, which all have important inflammatory components in their etiology. Glucocorticoids are the primary physiological anti-inflammatory horm...
ORGANISM(S): Rattus norvegicus 
2010-10-01 | E-GEOD-13461 | biostudies-arrayexpress
Methylation profilingEpigenetics is implicated in the basis of gender incongruence. An epigenome-wide association analysis.
The main objective was to carry out a global DNA methylation analysis in a population with gender incongruence before gender-affirming hormone treatment (GAHT), in comparison to a cisgender population.
ORGANISM(S): Homo sapiens 
2021-04-27 | GSE173382 | GEO
TranscriptomicsCSF2 x gender interactions on the transcriptome of Day 15 bovine extra-embryonic membrane
We aimed to study the effects of CSF2 treatment on the transcriptome of the Day 15 female and male embryo. Within the raw files, channel 1= Cy3 and channel 2= Cy5 Transcriptional profiling of bovine extra-embryonic membrane at Day 15 post-insemination produced by IVF. Oocytes were matured and ferti...
ORGANISM(S): Bos taurus 
2014-10-01 | E-GEOD-55364 | biostudies-arrayexpress
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