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MetabolomicsThe Immediate Metabolomic Effects of Whole Genome Duplication in the Greater Duckweed Spirodela polyrhiza

We use untargeted metabolomics to investigate the immediate phytochemical effects of autopolyploidy on our model system, the greater duckweed Spirodela polyrhiza, a small aquatic macrophyte from the family Lemnaceae. We compare metabolite abundances in four genetically distinct diploid-a...

2024-09-16 | MTBLS10435 | MetaboLights
TranscriptomicsGene duplication of type-B ARR transcription factors systematically extends transcriptional regulatory structures in Arabidopsis
Many of duplicated genes are enriched in signaling pathways. Recently, gene duplication of kinases has been shown to provide genetic buffering and functional diversification in cellular signaling. Transcription factors (TFs) are also often duplicated. However, how duplication of TFs affects their re...
ORGANISM(S): Arabidopsis thaliana 
2015-02-03 | E-GEOD-62597 | biostudies-arrayexpress
TranscriptomicsLineage-specific gene duplication and loss in human and great ape evolution
Given that gene duplication is a major driving force of evolutionary change and the key mechanism underlying the emergence of new genes and biological processes, this study sought to use a novel genome-wide approach to identify genes that have undergone lineage-specific duplications or contractions ...
ORGANISM(S): Homo sapiens 
2006-01-05 | E-GEOD-3980 | biostudies-arrayexpress
UnknownThe exon 13 duplication in the BRCA1 gene is a founder mutation present in geographically diverse populations. The BRCA1 Exon 13 Duplication Screening Group.
Not available
S-EPMC1287079 | biostudies-literature
TranscriptomicsTLR7 gene duplication accelerates autoimmunity and promotes nucleolar-specific B cells
Systemic autoimmune diseases such as lupus and scleroderma are characterized by the loss of tolerance to nuclear antigens, but the mechanisms by which specific autoantibodies are selected are unclear. Here we report that B cells containing the Y-linked autoimmune accelerator (Yaa) locus are intrins...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-4445 | biostudies-arrayexpress
TranscriptomicsT (Brachyury) gene duplication confers major susceptibility to familial chordoma
Using high-resolution array-CGH, we identified unique duplications of a region on 6q27 in four multiplex (≥ with ≥ 3 cases) families of chordoma, a cancer of presumed notochordal origin. comparison of test samples from chordoma families to a reference DNA sample
ORGANISM(S): Homo sapiens 
2009-10-04 | E-GEOD-17668 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 5 hominid species, including humans
Given that gene duplication is a major driving force of evolutionary change and the key mechanism underlying the emergence of new genes and biological processes, this study sought to use a novel genome-wide approach to identify genes that have undergone lineage-specific duplications or contractions ...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-SMDB-2855 | biostudies-arrayexpress
GenomicsMonkeypox virus gene duplication and loss
Possible adaption of the 2022 Monkeypox virus to the human host through gene duplication and loss
PRJEB56807 | ENA
ProteomicsISAba1 mediated intrinsic chromosomal oxacillinase duplication conveys carbapenem resistance
Tandem duplication of carbapenemase genes amplifies the gene copy number and enhances carbapenem resistance. These amplifications are often heterogenous, transient, locate in plasmids, which often also contribute to heteroresistance. The duplication is especially important for low-hydrolysis activit...
ORGANISM(S): Acinetobacter Baumannii 470922 
2023-01-17 | PXD039528 |
GenomicsGene expression variation during grape genome duplication
Gene expression variation during grape genome duplication
PRJNA489259 | ENA
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