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TranscriptomicsTranscription profiling of human THP-1 cells wild type vs overexpressing GAM or siRNAs directed against GAM (siGAM) challenged by LPS
24 hours following transfection with either a control mix, a construct overexpressing GAM or siRNAs directed against GAM (siGAM), THP-1 cells were challenged with LPS 100 ng/ml. RNAs were analyzed after 6 hours of LPS challenge
ORGANISM(S): Homo sapiens 
2010-06-09 | E-TABM-868 | biostudies-arrayexpress
ProteomicsExtensive folding variability between homologous chromosomes in mammalian cells
Genetic variation and 3D chromatin structure have major roles in gene regulation. Structural differences between genotypically different chromosomes and their effects on gene expression remain ill understood, due to challenges in mapping 3D genome structure with allele-specific resolution. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-30 | PXD048969 | Pride
Lc-msms Genome architecture mapping (gam) Chromatin Polycomb 
UnknownComplex multi-enhancer contacts captured by genome architecture mapping.
Not available
S-EPMC5366070 | biostudies-literature
OtherMultiplex GAM datasets collected with an average of three nuclear profiles each
Technologies for measuring 3D genome topology are increasingly important for studying mechanisms of gene regulation, for genome assembly and for mapping of genome rearrangements. We developed multiplex-GAM, a faster and more affordable version of Genome Architecture Mapping (GAM), a ligation-free te...
ORGANISM(S): Mus musculus 
2022-06-13 | GSE166380 | GEO
OtherMultiplex GAM datasets collected with an average of three nuclear profiles each (samples failing QC)
Technologies for measuring 3D genome topology are increasingly important for studying mechanisms of gene regulation, for genome assembly and for mapping of genome rearrangements. We developed multiplex-GAM, a faster and more affordable version of Genome Architecture Mapping (GAM), a ligation-free te...
ORGANISM(S): Mus musculus 
2022-06-13 | GSE166379 | GEO
UnknownMultiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C.
Not available
S-EPMC10333126 | biostudies-literature
UnknownGAMIBHEAR: whole-genome haplotype reconstruction from Genome Architecture Mapping data.
Not available
S-EPMC8504635 | biostudies-literature
GenomicsMultiplex GAM datasets collected with an average of three nuclear profiles each
Multiplex GAM datasets collected with an average of three nuclear profiles each
PRJNA700651 | ENA
GenomicsThree-dimensional genome structures of single mammalian sperm [GAM]
Three-dimensional genome structures of single mammalian sperm [GAM]
PRJNA1160225 | ENA
UnknownDissecting the cosegregation probability from genome architecture mapping.
Not available
S-EPMC9674989 | biostudies-literature
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