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MetabolomicsThe genomic and enzymatic basis for iridoid biosynthesis in cat thyme (Teucrium marum)
Iridoids are non-canonical monoterpenoids produced by both insects and plants. An example is the cat attracting and insect repelling volatile iridoid nepetalactone, produced by Nepeta sp. (catmint) and aphids. Recently, both nepetalactone biosynthetic pathways were elucidated, showing a remarkable c...
2026-04-20 | MTBLS9357 | MetaboLights
MetabolomicsGenomic and lipidomic actions of nandrolone on detached rotator cuff muscle in sheep
Reversal of fatty infiltration of pennate rotator cuff muscle after tendon release is hitherto impossible. The administration of nandrolone starting at the time of tendon release prevents the increase in fat content, but does not revert established fatty infiltration. We hypothesised that tendon rel...
2017-07-14 | MTBLS322 | MetaboLights
MetabolomicsAn integrated genomic and metabolomic approach for defining survival time in adult oligodendrogliomas patients

INTRODUCTION: The identification of frequent acquired mutations shows that patients with oligodendrogliomas have divergent biology with differing prognoses regardless of histological classification. A better understanding of molecular features as well as their metabolic pathways...

2021-10-06 | MTBLS869 | MetaboLights
MetabolomicsNatural variation of root exudates in Arabidopsis thaliana-linking metabolomic and genomic data
The 19 parent lines of the Arabidopsis thaliana MAGIC collection show significant differences in their root exudate profiles. Changes in metabolism were analyzed by ultra-performance liquid chromatography coupled to electrospray ionization quadrupole time–of–flight mass spectrometry (UPLC-ESI-QTOF-M...
2017-02-03 | MTBLS160 | MetaboLights
MetabolomicsIntegrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent

Leishmania donovani is the responsible agent for visceral leishmaniasis (VL) in the Indian subcontinent (ISC). The disease is lethal without treatment and causes 0.2 to 0.4 million cases each year. Recently, reports of VL in Nepalese hilly districts have increased as well as VL cases cau...

2022-09-15 | MTBLS1606 | MetaboLights
MetabolomicsAroma and quality of breads baked from old and modern wheat varieties and their prediction from genomic and flour-based metabolite profiles
Bread aroma is the principal characteristic perceived by the consumer yet it is mostly disregarded in the product chain. The main aim of this study was to evaluate the potential to include bread aroma as a new target criterion into the wheat product chain. The objectives of our study were to (i) qua...
2019-11-12 | MTBLS1187 | MetaboLights
MetabolomicsNatural genetic variation in C. elegans identified genomic loci controlling metabolite levels
Not available
ORGANISM(S): Caenorhabditis elegans 
ST000999 | MetabolomicsWorkbench
MetabolomicsHaplotype-resolved female and male genomes reveal sex-specific genomic regions and provide insights into thermal stress in Scapharca subcrenata

Integrated analyses of transcriptomic, proteomic and metabolomic data sets consistently highlights the crucial involvement of protein function and retinol metabolism pathways in the heat-resistant strain of S. subcrenata. These findings underscore the significance of these pathways in e...

2024-11-11 | MTBLS11038 | MetaboLights
MetabolomicsCombined functional genomic and metabolomic approaches identify new genes required for growth in human urine by multidrug resistant Escherichia coli ST131
Urinary tract infections (UTIs) are one of the most common bacterial infections in humans, with ~400 million cases across the globe each year. Uropathogenic E. coli (UPEC) is the major cause of UTI and increasingly associated with antibiotic resistance. This scenario has been worsened by the emergen...
2024-02-09 | MTBLS9131 | MetaboLights
MetabolomicsIntegrated Multilayer Omics Reveals the Genomic, Proteomic and Metabolic Influences of the Histidyl Dipeptides on Heart
Not available
ORGANISM(S): Mus musculus 
ST002056 | MetabolomicsWorkbench
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