Genotoxins - OmicsDI

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Transcription profiling by array of human HepG2 cells treated with false positive genotoxins, true genotoxins and non-genotoxins

In this study we aimed to identify the molecular pathways modified by the false positive genotoxins Quercetin, 8-Hydroxyquinoline and 17beta-Estradiol that may explain their in vitro genotoxic and their in vivo non-genotoxic effects, by combining in vitro transcriptomics with phenotypic data. The ef...

ORGANISM(S): Homo sapiens

2011-01-01 | E-MEXP-2574 | biostudies-arrayexpress

Delivery, structure, and function of bacterial genotoxins.

Not available

S-EPMC9341358 | biostudies-literature

Bacterial Genotoxins: Merging the DNA Damage Response into Infection Biology.

Not available

S-EPMC4598774 | biostudies-literature

Genotoxins: The Mechanistic Links between Escherichia coli and Colorectal Cancer.

Not available

S-EPMC9954437 | biostudies-literature

APOBEC3C, a perinucleolar protein induced by genotoxins, is recruited to DNA damage sites

The human genome contains 11 APOBEC (Apolipoprotein B mRNA Editing Catalytic Polypeptide-like) cytidine deaminases classified into four families. These proteins function mainly in innate antiviral immunity and can also restrict endogenous retrotransposable element multiplication. The present study f...

ORGANISM(S): Homo sapiens (Human)

2022-02-07 | PXD020105 | Pride