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TranscriptomicsGeranylgeranylacetone and geranylgeraniol effects on HEPG2 cells
HepG2 cells (5 × 10⁵ cells/mL; 1 mL per well) were seeded in 24-well plates. The following day, the cells were exposed to 50 µM geranylgeraniol (B1,B2,B3), 40 µM geranylgeranylacetone (C1,C2,C3), or vehicle control, ethanol (A1,A2,A3). Each condition was tested in triplicate. After 24 h of treatment...
ORGANISM(S): Homo sapiens 
2026-08-07 | E-MTAB-17441 | biostudies-arrayexpress
TranscriptomicsCompare RNA profile between LPS+CPN and LPS+CPN+GGOH treated peritoneal macrophages
To find out genes regulated by geranylgeraniol (GGOH) treatment in peritoneal macrophage, we compared gene expression of cells treated with 200ng ml LPS and 250 micromolar compactin versus 200ng ml LPS, 250 micromolar compactin and 100micromolar GGOH. To find out upregulated or downregulated genes r...
ORGANISM(S): Mus musculus 
2013-11-12 | E-GEOD-48646 | biostudies-arrayexpress
GenomicsGeranylgeranylacetone and geranylgeraniol effects on HEPG2 cells
Geranylgeranylacetone and geranylgeraniol effects on HEPG2 cells
PRJEB123246 | ENA
UnknownBiphasic requirement for geranylgeraniol in hippocampal long-term potentiation.
Not available
S-EPMC2516227 | biostudies-literature
UnknownBrain cholesterol turnover required for geranylgeraniol production and learning in mice.
Not available
S-EPMC1450160 | biostudies-literature
UnknownDietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer.
Not available
S-EPMC5511264 | biostudies-literature
UnknownGeranylgeraniol and Neurological Impairment: Involvement of Apoptosis and Mitochondrial Morphology.
Not available
S-EPMC4813225 | biostudies-literature
UnknownSufficient production of geranylgeraniol is required to maintain endotoxin tolerance in macrophages.
Not available
S-EPMC3826689 | biostudies-literature
UnknownEmulsion-structured pectin-based edible films with whey protein and short-chain dietary fibers for geranylgeraniol encapsulation and strawberry preservation.
Not available
S-EPMC12398898 | biostudies-literature
GenomicsNone
Microbiome changes after geranylgeraniol supplementation in high-fat diet-induced obese mice
PRJNA637806 | ENA
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