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TranscriptomicsCSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline
P granules in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency.  Sterility in the absence of P granules is often accompanied by the mis-expression of soma-specific proteins and the initiation of somatic differentiation in germ cells.  To investigate ...
ORGANISM(S): Caenorhabditis elegans 
2015-05-20 | E-GEOD-67954 | biostudies-arrayexpress
TranscriptomicsDEPS-1 promotes P granule assembly and RNA interference in C. elegans germ cells
P granules are germ-cell-specific cytoplasmic structures containing RNA and protein and required for proper germ cell development in C. elegans. A new P-granule-associated protein, DEPS-1, whose loss disrupts P granule structure and function was analysed in this study. Genome wide analysis of gene...
ORGANISM(S): Caenorhabditis elegans 
2010-05-26 | E-GEOD-9993 | biostudies-arrayexpress
GenomicsGerm Granules Govern Small RNA Inheritance
Germ Granules Govern Small RNA Inheritance
PRJNA526484 | ENA
ProteomicsProximity labeling identifies LOTUS domain proteins that promote the formation of perinuclear germ granules in C. elegans
Using C. elegans germ granule, called P granule, as a model system, we employed a proximity-based labeling method in combination with mass spectrometry to comprehensively define its protein components. This set of experiments identified over 200 proteins, many of which contain intrinsically disorder...
ORGANISM(S): Caenorhabditis elegans 
2021-11-11 | PXD027998 | Pride
Proximity labeling Germ granules C. elegans 
GenomicsGerm granules coordinate RNA-based epigenetic inheritance pathways
Germ granules coordinate RNA-based epigenetic inheritance pathways
PRJNA556040 | ENA
UnknownControl over the morphology and segregation of Zebrafish germ cell granules during embryonic development.
Not available
S-EPMC2441585 | biostudies-literature
GenomicsC. elegans germ granules regulate both germline and somatic RNAome [RNA-Seq]
C. elegans germ granules regulate both germline and somatic RNAome [RNA-Seq]
PRJNA951746 | ENA
GenomicsC. elegans germ granules regulate both germline and somatic RNAome [miRNA-Seq]
C. elegans germ granules regulate both germline and somatic RNAome [miRNA-Seq]
PRJNA951743 | ENA
GenomicseIF4e Assembly into Germ Granules is Essential for its Repressive Function
eIF4e Assembly into Germ Granules is Essential for its Repressive Function
PRJNA1274489 | ENA
UnknownGerm granules in development.
Not available
S-EPMC10165536 | biostudies-literature
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