Germline genes - OmicsDI

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Organisms

Homo sapiens (883)
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Oikopleura dioica (2)
Candida albicans WO-1 (2)

Organisms

Mus musculus (363)
Homo sapiens (336)
Caenorhabditis elegans (187)
Drosophila melanogaster (121)
Arabidopsis thaliana (18)
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Zea mays subsp. mays x Zea mays subsp. mexicana (5)
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Stylonychia lemnae (1)
Eptatretus atami (1)
Manduca sexta (1)
Monomorium pharaonis (1)

Repository

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biostudies-arrayexpress (1074)
geo (990)
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pride (57)
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Tissue

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Sindbis virus + non-specific RNA (1)
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Technology Type

Mass Spectrometry (57)
Shotgun proteomics (26)
Illumina HiSeq 2000 (15)
Affinity purification coupled with mass spectrometry proteomics (13)
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Data-dependent acquisition (5)
Mass spectrometry (4)
Data-independent acquisition (3)
SWATH MS (3)
Illumina HiSeq 2500 (2)
Illumina HiSeq 2000, ILLUMINA (2)
Affinity proteomics (2)
ILLUMINA, Illumina HiSeq 2500, HiSeq X Ten (1)
Affymetrix OncoScan FFPE Express (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000, Illumina MiSeq, ILLUMINA (1)
NextSeq 500, Illumina HiSeq 2500, AB 5500xl Genetic Analyzer, ILLUMINA (1)
Ion Torrent Proton, Illumina HiSeq 2000 (1)
454 GS FLX Titanium, Illumina HiSeq 2000 (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina HumanCNV370, Illumina HumanHap 300 v2 Duo, Taqman and sequencing, Illumina Human660W-Quad (1)
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Instrument Platform

Illumina HiSeq 2500 (12)
Illumina HiSeq 2000 (12)
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NextSeq 500 (6)
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Axon- GenePix4000B (2)
G2505B DNA microarray scanner (2)
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Agilent G2565BA Microarray Scanner System (Agilent Technologies, Santa Clara, CA) (1)
Tecan HS4800 hybridization station (Tecan, Vienna, Austria) (1)
Agilent DNA Microarray Scanner Model #G2565BA (1)
IScan (Illumina) (1)
454 GS FLX (1)
Complete Genomics (1)
Qiagen MinElute (1)
ScanArray scanning hardware (1)
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GenePix 4000A [Axon Instruments] (1)
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Publication Date

2010 (227)
2014 (223)
2011 (159)
2013 (157)
2012 (156)
2015 (130)
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2025 (116)
2021 (115)
2023 (107)
2008 (90)
2020 (86)
2009 (84)
2026 (80)
2016 (64)
2019 (57)
2022 (56)
2017 (56)
2018 (46)
2007 (41)
2005 (25)
2006 (23)
2004 (7)
2003 (6)
2001 (1)

UNIPROT ID/AC

A0A024RC46 (95)
A0A087WTX5 (95)
A0A087WVW2 (95)
A0A087WXI0 (95)
A0A087WYL9 (95)
A0A087X130 (95)
A0A087X1V9 (95)
A0A0A0MS07 (95)
A0A0A0MS51 (95)
A0A0B4J1V0 (95)
A0A0C4DG89 (95)
A0AVT1 (95)
A0FGR8 (95)
A0FGR8-2 (95)
A0FGR8-6 (95)
A0M8Q6 (95)
A0N5G5 (95)
A1L0T0 (95)
A2BFH1 (95)
A2IPI2 (95)
A2IPI5 (95)
A2NB46 (95)
A2NKM6 (95)
A2NUT2 (95)
A2NXP9 (95)
A4F255 (95)
A5A3E0 (95)
A6NHL2 (95)
A6NNZ2 (95)
A8MTJ3 (95)

ENSEMBL ID

ENSG00000170477 (95)
ENSG00000229353 (47)
ENSG00000147251 (18)
ENSG00000176092 (2)
ENSG00000247315 (1)

CHEBI ID

CHEBI:67040 (2)
CHEBI:17768 (2)
CHEBI:16927 (2)
CHEBI:26271 (2)
CHEBI:25094 (2)
CHEBI:17858 (2)
CHEBI:16856 (2)
CHEBI:18237 (2)
CHEBI:22653 (2)
CHEBI:16811 (2)
CHEBI:27470 (2)
CHEBI:17361 (2)
CHEBI:25017 (2)
CHEBI:16610 (2)
CHEBI:17509 (2)
CHEBI:7916 (2)
CHEBI:29016 (2)
CHEBI:16761 (2)
CHEBI:17345 (2)
CHEBI:27897 (2)
CHEBI:143106 (1)
CHEBI:81810 (1)
CHEBI:57600 (1)
CHEBI:166563 (1)
CHEBI:139445 (1)
CHEBI:41094 (1)
CHEBI:11596 (1)
CHEBI:46398 (1)
CHEBI:65180 (1)
CHEBI:57299 (1)

Metabolite Name

Folic acid (2)
Pantothenic acid (2)
N-Acetyl spermine (1)
N-Acetyl putrescine (1)
Cadaverin (1)
N-Acetyl spermidine (1)
Tiglyl-Carnitine (1)
5-methyl tetrahydrofolic acid (1)
Succinyl-coa (1)
5?-Methylthioadenosine (1)
Dimethyl arginine (1)
Guanosine-monohosphate (1)
Adenosine 5'-Triphosphate (1)
Cytidine Triphosphate (1)
SAM (1)
Uridine 5'-diphosphoglucuronic acid (1)
Glutamate internal standard(13C515N glutamate) (1)
2-hydroxyglutarate(2-) (1)
5'-Cytidylic Acid (1)
Guanosine-diphosphate (1)
Guanosine 5'-triphosphate (1)
SAH (1)
L-Glutathione (reduced) (1)
N-Acetyl-1-aspartylglutamic acid (1)
Riboflavine (1)
Uridine 5'-diphosphogalactose (1)
Cyclic ADP-ribose (1)
L-Glutathione oxidized (1)
Guanosine monophosphate (GMP) (1)
CoA (1)

First Public Date

2014 (174)
2024 (167)
2025 (151)
2023 (150)
2021 (140)
2026 (104)
2020 (96)
2022 (81)
2019 (77)
2017 (69)
2013 (61)
2015 (57)
2018 (53)
2016 (38)

Classification

helminths (3)

Study status

Recruiting (3)
Terminated (1)
Not provided (1)
Completed (1)

Study type

Transcription profiling by array (610)
RNA-seq of coding RNA (85)
Unknown experiment type (74)
Comparative genomic hybridization by array (70)
RNA-seq of non coding RNA (49)
ChIP-seq (40)
ChIP-chip by tiling array (18)
Genotyping by array (18)
Transcription profiling by tiling array (17)
DNA-seq (15)
Methylation profiling by high throughput sequencing (14)
Methylation profiling by array (13)
Other (8)
ChIP-chip by array (5)
RNAi profiling by array (4)
Genotyping by high throughput sequencing (4)
Animal - High-throughput sequencing (3)
MicroRNA profiling by array (3)
RNA-seq of total RNA (3)
Cell line - High-throughput sequencing (2)
Transcription profiling by RT-PCR (2)
CUT&RUN (2)
Transcription profiling by SAGE (1)
Cell line - Two-color microarray (1)
Human - Single-cell sequencing (1)
Human - High-throughput sequencing (1)
Plant - High-throughput sequencing (1)
Translation profiling (1)
High-throughput sequencing (1)
Spatial transcriptomics by high-throughput sequencing (1)

Release Date

2022 (598)
2021 (583)
2023 (514)
2020 (505)
2025 (448)
2024 (434)
2019 (419)
2018 (361)
2017 (348)
2015 (332)
2016 (308)
2014 (293)
2010 (287)
2013 (268)
2012 (262)
2011 (229)
2009 (153)
2008 (137)
2007 (69)
2006 (61)
2026 (46)
2005 (41)
2004 (21)
2003 (17)
2001 (14)
2002 (10)
2000 (10)
1998 (6)
1999 (3)
1993 (2)

Lab affiliation

CECAD Cluster of Excellence, University of Cologne (2)
Shanghai Jiao Tong University (2)
1Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, H3A 1A3, Canada 2Department of Biochemistry, McGill University, Montreal, QC, H3G 1Y6, Canada (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Assistant professor, School of Biological Sciences, Seoul National University. (1)
CNRS UMR7242, Biotechnology and Cell Signaling, 300 Bd Sébastien Brant, 67412 Illkirch Cedex, France University of Strasbourg (1)
CNRS UMR7242, Biotechnology and Cell Signaling, University of Strasbourg, 300 Bd Sébastien Brant, 67412 Illkirch, France (1)
CRUK Scotland Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
CSIR-Centre for Cellular and Molceular Biology, Hyderabad, India TIGS-Tata Institute for Genetics and Society ,Bengaluru, India (1)
Cancer Research UK Cambridge Institute University of Cambridge Li Ka Shing Centre Cambridge CB2 0RE United Kingdom (1)
Center for RNA Biology: From Genome to Therapeutics Department of Biochemistry and Biophysics University of Rochester Medical Center Rochester, NY, 14642, USA (1)
Center for Systems and Synthetic Biology Institute for Cellular and Molecular Biology Department of Molecular Biosciences University of Texas at Austin (1)
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne, Cologne, Germany. (1)
Deparment of Molecular Biology and Genetics Aarhus University, Denmark (1)
Department of Biochemistry and Molecular Biology, School of Life Sciences, Central South University, No. 172, Tongzipo road, Yuelu District, Changsha 410013, Hunan Province, China (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biochemistry, UC Riverside (1)
Department of Biological Sciences, University of Southern California, Los Angeles CA (1)
Department of Chemical & Systems Biology Stanford University USA (1)
Department of Chemical & Systems Biology, Stanford University, USA (1)
Department of Chemistry & Chemical Biology, Northeastern University (1)
Department of Gene Expression, Faculty of Biology, Adam Mickiewicz University in Poznan, Poznan, Poland (1)
Department of Human Genetics, University of Chicago, Chicago, Illinois, USA; Department of Medicine, University of Chicago, Chicago, Illinois, USA (1)
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Box 280, S-171 77 Stockholm, Sweden. (1)
Department of Molecular Biology and Genetics, Aarhus University, Denmark (1)
Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands (1)
Department of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, Germany (1)
Genomic Medicine Institute, Cleveland Clinic (1)
Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, GuangZhou, GuangDong, China (1)
Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China (1)

Location

United States (3)
China (1)
United Kingdom (1)
France (1)

Keyword

BRCA1 (2)
BRCA2 (2)
PARPi (1)
Rare tumor (1)
CO-338 (1)
Homologous recombination (1)
DNA repair (1)
LODESTAR (1)
Germline (1)
Somatic (1)
PALB2 (1)
RAD51C (1)
RAD51D (1)
BARD1 (1)
BRIP1 (1)
FANCA (1)
RAD51 (1)
RAD51B (1)
HRR (1)
Platinum sensitive (1)
Platinum resistant (1)
Tumor agnostic (1)
Basket trial (1)
Leiomyosarcoma (1)
Ampullary carcinoma (1)
Carcinosarcoma (1)
HRD (1)
Genome analysis (1)
Genetic modifiers (1)
Next generation sequencing (NGS) (1)

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Silencing of Germline-Expressed Genes by DNA Elimination in Somatic Cells

Chromatin diminution is the programmed elimination of specific DNA sequences during development. It occurs in diverse species, but the function(s) of diminution and the specificity of sequence loss remain largely unknown. Diminution in the nematode Ascaris suum occurs during early embryonic cleavage...

ORGANISM(S): Ascaris suum

2012-11-13 | E-GEOD-38470 | biostudies-arrayexpress

RNA-Seq to identify germline stem cell-enriched genes and cystoblast-enriched genes and BMP targeted genes

We sequenced the transcriptomes of genetically expanded stem cells that either experience high levels of BMP signalling (expression of constitutively active BMPR, tkvQD.) or low levels (expression of shRNA again the differentiation promoting factor bam). We also sequenced RNA from differentiating da...

ORGANISM(S): Drosophila melanogaster

2019-05-28 | E-MTAB-7063 | biostudies-arrayexpress

Human adult germline stem cells in question

Conrad et al. Nature 456, 344â€“349 (2008) have generated human adult germline stem cells (haGSCs) from human testicular tissue, which they claim have similar pluripotent properties to human embryonic stem cells (hESCs). Here we investigate the pluripotency of haGSCs by using global gene-expression ...

ORGANISM(S): Homo sapiens

2010-07-29 | E-GEOD-17772 | biostudies-arrayexpress

Systematic identification of factors involved in the silencing of germline genes in mouse embryonic stem cells

In mammals, many germline genes are repressed by epigenetic mechanisms to prevent their illegitimate expression in embryonic and somatic cells. To advance our understanding of the complete mechanisms restricting the expression of germline genes in mammals, we analyzed the chromatin signature of germ...

ORGANISM(S): Mus musculus (Mouse)

2023-02-03 | PXD030666 | Pride

Pluripotent embryonic stem cells and multipotent adult germline stem cells reveal similar transcriptomes including pluripotency-related genes

DNA microarray analysis was performed with mouse multipotent adult germline stem cells (maGSCs) and embryonic stem cells (ESCs) from different genetic backgrounds cultured under standard ESC culture conditions and under differentiation-promoting conditions by the withdrawal of Leukemia Inhibitory Fa...

ORGANISM(S): Mus musculus

2010-07-12 | E-GEOD-22605 | biostudies-arrayexpress

Prepubertal Human Spermatogonia and Mouse Gonocytes Share Conserved Gene Expression of Germline Stem Cell Regulatory

Full title: Prepubertal Human Spermatogonia and Mouse Gonocytes Share Conserved Gene Expression of Germline Stem Cell Regulatory Molecules Oligonucleotide Microarray Analysis Reveals Novel Genes Expressed in Prepubertal Human Spermatogonia and Mouse Gonocytes Four hundred cells were selected for ea...

ORGANISM(S): Homo sapiens

2009-11-06 | E-GEOD-18914 | biostudies-arrayexpress

DRM complex mutant lin-54 vs. H3K36 methyltransferase mutant mes-4 vs. lin-54; mes-4 double mutant vs. wild type C.elegans germline

Here we uncover antagonistic regulation of transcript levels in the germline of Caenorhabditis elegans hermaphrodites. The histone methyltransferase MES-4 marks genes expressed in the germline with methylated Lys36 on histone H3 (H3K36me) and promotes their transcription; MES-4 also represses genes ...

ORGANISM(S): Caenorhabditis elegans

2013-11-05 | E-GEOD-52064 | biostudies-arrayexpress

Distinctive regulatory architectures of ubiquitous, germline and somatic genes

PRJNA592702 | ENA

Distinctive regulatory architectures of ubiquitous, germline and somatic genes

PRJNA592701 | ENA

Germline Genetic Variants in Cancer-Susceptibility Genes in Patients With Osteosarcoma

PRJNA733249 | ENA

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