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The Protein Phosphatase type 1 catalytic subunit (PP1c) works in combination with an array of regulatory proteins to specifically dephosphorylate a diverse range of substrates in the cell. In the human malaria parasite, Plasmodium falciparum, this phosphatase and its regulators are poorly character...
ORGANISM(S): Mus musculus (Mouse) Plasmodium falciparum (isolate 3D7) 
2023-10-24 | PXD042114 | Pride
The essential and distinct functions of Protein Phosphatase type 1 (PP1) catalytic subunit in eukaryotes are exclusively achieved through its interaction with a myriad of regulatory partners. In this work, we report the molecular and functional characterization of Gametocyte EXported Protein 15 (GEX...
ORGANISM(S): Plasmodium berghei ANKA 
2019-07-16 | PXD013874 | Pride
In the absence of an effective vaccine and the emerging resistance to artemisinin combination therapy, malaria is still a significant threat to human health. Increasing our understanding of the specific mechanisms of the biology of Plasmodium is essential to propose new strategies to control this in...
ORGANISM(S): Mus musculus (Mouse) 
2019-07-16 | PXD013814 | Pride
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