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ProteomicsExploration of GFP-IRF7 neddylation sites
To explore the possible neddylation sites, GFP-IRF7 and His-NEDD8 were co-overexpressed in HEK293 cell line and GFP was immunoprecipitated, followed by SDS-PAGE and silver staining. The band detected was subjected to LC–MS/MS.
ORGANISM(S): Mus musculus (Mouse) 
2021-08-19 | PXD024052 | Pride
Hek293 Gfp-irf7 Lc-ms/ms 
UnknownSwine IRF3/IRF7 attenuates inflammatory responses through TLR4 signaling pathway.
Not available
S-EPMC5617478 | biostudies-literature
UnknownFunctional characterization of goose IRF1 in IFN induction and anti-NDV infection.
Not available
S-EPMC8981851 | biostudies-literature
TranscriptomicsEngineering a haematopoietic stem cell niche by reprogramming mesenchymal stromal cells (RNA-Seq)
Haematopoietic stem cells (HSCs) reside in bone marrow (BM) niches where they are maintained to replenish all blood cell lineages throughout life. Among the constituents of the murine HSC niches, various cell types such as CXCL12-abundant reticular (CAR) cells, Nestin-GFP+ perivascular cells, leptin...
ORGANISM(S): Mus musculus 
2019-04-05 | GSE112232 | GEO
GenomicsEngineering a haematopoietic stem cell niche by reprogramming mesenchymal stromal cells (ATAC-Seq)
Haematopoietic stem cells (HSCs) reside in bone marrow (BM) niches where they are maintained to replenish all blood cell lineages throughout life. Among the constituents of the murine HSC niches, various cell types such as CXCL12-abundant reticular (CAR) cells, Nestin-GFP+ perivascular cells, leptin...
ORGANISM(S): Mus musculus 
2019-04-05 | GSE112231 | GEO
GenomicsSerine/arginine-rich splicing factor 7 (SRSF7) promotes the type I interferon response by activating Irf7 transcription
Serine/arginine-rich splicing factor 7 (SRSF7) promotes the type I interferon response by activating Irf7 transcription
PRJNA1070697 | ENA
UnknownEngineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells.
Not available
S-EPMC6499646 | biostudies-literature
TranscriptomicsTranscription profiling of human and mouse keratinocytes infected with AD and Ad-NotchIC viruses reveals cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
Notch signaling promotes commitment of keratinocytes to differentiation and suppresses tumorigenesis. p63, a p53 family member, has been implicated in establishment of the keratinocyte cell fate and/or maintenance of epithelial self-renewal. Here we show that p63 expression is suppressed by Notch1 a...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5229 | biostudies-arrayexpress
TranscriptomicsEffect of miR-144 and miR-451 expression on lung epithelial cell responses to influenza infection at 1 and 18 hours.
Antiviral responses must be regulated to rapidly defend against infection while minimizing inflammatory damage, but the mechanisms for establishing the magnitude of response within an infected cell are not well understood. miRNAs are small non-coding RNAs that negatively regulate protein levels by b...
ORGANISM(S): Mus musculus 
2013-09-11 | E-GEOD-50742 | biostudies-arrayexpress
UnknownBSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein.
Not available
S-EPMC9367692 | biostudies-literature
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