Sort   by:  
 Page size 
TranscriptomicsTimecourse of mCMV Infection of Bone Marrow-Derived Macrophages (BMDMs)
The systematic temporal gene expression analysis of primary macrophages activated under immune (interferon-gamma) and productive viral infection with murine cytomegalovirus (mCMV). The primary objective of the study is to define, in an unbiased manner, cause-and-effect relationships in the program o...
ORGANISM(S): Mus musculus 
2015-07-10 | E-GEOD-42503 | biostudies-arrayexpress
TranscriptomicsTimecourse of Interferon-Gamma Treatment of Bone Marrow-Derived Macrophages (BMDMs)
The systematic temporal gene expression analysis of primary macrophages activated under immune (interferon-gamma (IFN-g)) and productive viral infection with murine cytomegalovirus (mCMV). The primary objective of the study is to define, in an unbiased manner, cause-and-effect relationships in the p...
ORGANISM(S): Mus musculus 
2015-07-10 | E-GEOD-42504 | biostudies-arrayexpress
ModelsBenson2017 - Systems Pharmacology Multidrug (cholesterol biosynthesis pathway)
BensonWattersonetal_SystemsPharmacology_Multidrug This model is described in the article: Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway. Benson H, Watterson S, Sharman J, Mpamhanga C, Parton A, Southan C, Ha...
2017-09-26 | MODEL1506220000 | BioModels
UnknownCD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses.
Not available
S-EPMC9640663 | biostudies-literature
ModelsMODEL1207300000_url.xml
This model is from the article: A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction. Watterson S, Guerriero ML, Blanc M, Mazein A, Loewe L, Robertson KA, Gibbs H, S...
2005-01-01 | MODEL1207300000 | BioModels
TranscriptomicsDissecting primary (translation independent) from secondary (translation dependent) IFN-mediated differential gene expression
NIH-3T3 cells were pretreated for 15 min with either DMSO (mock) or cycloheximide followed by addition of either mock, 100 U/ml IFNalpha or 100 U/ml IFNgamma for 1h. During the last 30 min, 500 µM 4-thiouridine was added to cell culture medium. Total cellular RNA was isolated using Trizol reagent an...
ORGANISM(S): Mus musculus 
2013-07-04 | E-GEOD-30457 | biostudies-arrayexpress
TranscriptomicsExpression data from primary human dermal fibroblasts with STAT2 deficiency and control fibroblasts treated with interferon
Primary human dermal fibroblasts were isolated from an individual showing a genetic defect in innate antiviral immunity associated with profound failure of type 1 interferon signaling and absence of the STAT2 protein. The transcriptional response of these cells to a 10h treatment with interferon-alp...
ORGANISM(S): Homo sapiens 
2013-03-05 | E-GEOD-41960 | biostudies-arrayexpress
TranscriptomicsWhole blood transcriptional analysis of vaccine combination administration in infants
We aimed to identify the gene network and pathway biology associated with response to vaccine administration by determining genome-wide alterations in host RNA in children Samples were obtained from children before and after vaccine administration. RNA was extracted from whole blood samples with PAX...
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-83951 | biostudies-arrayexpress
UnknownSwi4-dependent SWI4 transcription couples cell size to cell cycle commitment.
Not available
S-EPMC11930368 | biostudies-literature
TranscriptomicsTranscription profiling time series of mouse bone marrow derived macrophages after interferon-gamma treatment
We have examined the transcriptional events in mouse bone marrow derived macrophages (MBDM) with interferon-gamma (Ifng)at 2, 4 & 8 h following treatment or pre-treatment (0 h).
ORGANISM(S): Mus musculus 
2008-03-18 | E-MEXP-1490 | biostudies-arrayexpress
Sort   by:  
 Page size