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TranscriptomicsGene expression profile of C1013G/CXCR4 mutated WM cells
C1013G/CXCR4 variant has been inserted into BCWM.1 cells, and gene expression profile has been performed on the mutated cells and on the parental cells. Affimetrix Human Genome U133_Plus2.0 array We used microarrays to dissect the possible changes occurring at mRNA level in mutated cells versus the ...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-50683 | biostudies-arrayexpress
UnknownMulticenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma.
Not available
S-EPMC2799050 | biostudies-literature
UnknownDistinct roles of class I PI3K isoforms in multiple myeloma cell survival and dissemination.
Not available
S-EPMC4003418 | biostudies-literature
UnknownDeeper response predicts better outcomes in high-risk-smoldering-myeloma: results of the I-PRISM phase II clinical trial.
Not available
S-EPMC11698957 | biostudies-literature
UnknownA Phase I/II Study of Evofosfamide, A Hypoxia-activated Prodrug with or without Bortezomib in Subjects with Relapsed/Refractory Multiple Myeloma.
Not available
S-EPMC6335171 | biostudies-literature
UnknownCitron Rho-interacting kinase silencing causes cytokinesis failure and reduces tumor growth in multiple myeloma.
Not available
S-EPMC6457230 | biostudies-literature
UnknownProgression signature underlies clonal evolution and dissemination of multiple myeloma.
Not available
S-EPMC8085483 | biostudies-literature
UnknownGenomic Landscape of Waldenstrom Macroglobulinemia and Its Impact on Treatment Strategies.
Not available
S-EPMC7351339 | biostudies-literature
ProteomicsMapping the Degradable Kinome: A Resource for Expedited Degrader Development
Targeted protein degradation refers to the use of small molecule inducers of ubiquitin-dependent degradation of proteins and enables the development of drugs to previously inaccessible targets. Degrader development is an empirical process due to a poor understanding of the key properties that requi...
ORGANISM(S): Homo sapiens (Human) 
2021-01-18 | PXD021313 | Pride
Ubiquitin E3 ligase. Ubiquitin proteasome system Protac Imid Degrader Targeted degradation Kinase 
ProteomicsMapping the Degradable Kinome: A Resource for Expedited Degrader Development
Targeted protein degradation refers to the use of small molecule inducers of ubiquitin-dependent degradation of proteins and enables the development of drugs to previously inaccessible targets. Degrader development is an empirical process due to a poor understanding of the key properties that requi...
ORGANISM(S): Homo sapiens (Human) 
2021-04-06 | PXD021255 | Pride
Ubiquitin Ubiquitin proteasome system Protac Imid Degrader Targeted degradation E3 ligase Kinase 
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