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Discriminating pathogenic bacteria from energy-harvesting commensals is key to host immunity. Using mutants defective in the enzymes of O-linked N-acetylglucosamine (O-GlcNAc) cycling, we examined the role of this nutrient-sensing pathway in the Caenorhabidits elegans innate immune response. Using w...
ORGANISM(S): Caenorhabditis elegans 
To determine the physiological targets of the NELF complex, and provide insight into the mechanism of NELF activity in vivo. Experiment Overall Design: Drosophila melanogaster S2 cells, obtained from the Drosophila Genomics Resource Center, were untreated, or treated with dsRNA for 72 hours, as desc...
ORGANISM(S): Drosophila melanogaster 
Regulation of gene expression programs is crucial for the survival of microbial pathogens in host environments and for their ability to cause disease. Here we investigated the epigenetic regulator RSC (Remodels the Structure of Chromatin) in the most prevalent human fungal pathogen Candida albicans....
ORGANISM(S): Candida albicans (Yeast) 
2020-11-11 | PXD017990 | Pride
Regulation of gene expression programs is crucial for the survival of microbial pathogens in host environments and for their ability to cause disease. In this study, we investigated the epigenetic regulator RSC (Remodels the Structure of Chromatin) in the most prevalent human fungal pathogen Candida...
ORGANISM(S): Candida albicans (Yeast) 
2020-11-11 | PXD017987 | Pride
Regulation of gene expression programs is crucial for the survival of microbial pathogens in host environments and for their ability to cause disease. Here we investigated the epigenetic regulator RSC (Remodels the Structure of Chromatin) in the most prevalent human fungal pathogen Candida albicans....
ORGANISM(S): Candida albicans (Yeast) 
2020-11-11 | PXD017988 | Pride
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